SOLICITATION NOTICE
A -- Development of Enrichment and Selective Culture Media for the Isolation of Special Pathogens from High Priority Foods
- Notice Date
- 5/30/2003
- Notice Type
- Solicitation Notice
- Contracting Office
- Department of Health and Human Services, Food and Drug Administration, Division of Construction and Agency Support Contracting, 5630 Fishers Lane, Room 2129, Rockville, MD, 20857-0001
- ZIP Code
- 20857-0001
- Solicitation Number
- 223-03-2487
- Response Due
- 7/15/2003
- Point of Contact
- Ed Arnold, Contract Specialist, Phone (301) 827-7161, Fax (301) 827-7151, - Hamilton Brown, Contract Specialist, Phone (301) 827-7043, Fax (301) 827-7101,
- E-Mail Address
-
earnold@oc.fda.gov, hbrown@oc.fda.gov
- Description
- The Food and Drug Administration, Center for Food Safety and Applied Nutrition, has a requirement for a formal proposal. This synopsis seeks to identify the interest from potential contractors for the “Development of Enrichment and Selective Culture Media for the Isolation of Special Pathogens from High Priority Foods.” Recent events have reinforced the importance of FDA’s long-standing interest in the development of improved methods for the identification of potential threat agents in foods. CFSAN maintains an active research program for developing and enhancing methodologies to detect and identify microbial hazards that may contaminate food and food products either naturally or through deliberate contamination. Standard protocols for isolation of the most commonly occurring pathogens have been developed. Traditionally, these protocols rely on enrichment and selective culture media for the isolation of a pathogen from the food. CFSAN needs to further enhance its detection and identification capabilities with respect to pathogens that are not typically considered to be foodborne pathogens. Specifically, there is a need to develop bacterial growth media that will improve the recovery of these atypical pathogens from priority food matrices. Initial efforts will focus specifically in the detection of Brucella and Burkholderia species associated with human disease. Statement of Work The contract shall include preliminary assessment of growth and isolation characteristics of pure culture isolates in media from commercial or other sources. Furthermore, selected media preparations which have been found to hold the greatest promise for fulfillment of the goals will be evaluated for use with representative food matrix categories of interest. Independently and not as an agent of the Government, the contractor shall furnish the necessary personnel, materials, services, facilities, and otherwise do all things necessary for or incident to the performance of the work. The contractor shall work closely with CFSAN throughout this requirement. All services shall be provided in a timely manner to help ensure that CFSAN can fulfill its regulatory responsibilities and guard the American public from intentional or accidental contamination of the food supply with these microbiological agents. Task 1 Initially the contractor shall identify those liquid and solid, enrichment and selective media that are available for culture of Brucella abortus, melitensis, and suis (Brucella spp.). These media formulations may be drawn from a number of sources, including, but not limited to commercially available media and the scientific literature. The contractor shall evaluate each solid selective and liquid culture medium formulation for its possible application in culturing Brucella spp. from foods that are representative of several food groups of interest to CFSAN. CFSAN will work with the contractor to identify specific food matrices to be used. It is intended that a few foods will be chosen as representatives of five general food categories or groups that may be defined either by dietary function, composition or storage conditions. For example, milk (high fat), powdered infant formula (dry product, consumption on relevant subpopulation), lettuce (leafy vegetable), shrimp salad (high fat, complex matrix), raspberries (fruit). Upon completion, the contractor shall consult with CFSAN regarding which media hold the greatest potential for use in enrichment and selective culture of Brucella spp. Those enrichment or selective culture media that demonstrate the greatest potential for use with different food matrices will be modified as needed to produce reliable media for enrichment and selective culture of Brucella spp. species from food. Task 2 Initially the contractor shall identify those liquid and solid, enrichment and selective media that are available for culture of Burkholderia mallei and pseudomallei (Burkholderia spp). These media formulations may be drawn from a number of sources, including, but not limited to commercially available media and the scientific literature. The contractor shall evaluate each solid selective and liquid culture medium formulation for its possible application in culturing Burkholderia spp. from foods that are representative of several food groups of interest to CFSAN. CFSAN will work with the contractor to identify specific food matrices to be used. It is intended that a few foods will be chosen as representatives of five general food categories or groups that may be defined either by dietary function, composition or storage conditions. For example, milk (high fat), powdered infant formula (dry product, consumption on relevant subpopulation), lettuce (leafy vegetable), shrimp salad (high fat, complex matrix), raspberries (fruit). Upon completion, the contractor shall consult with CFSAN regarding which media hold the greatest potential for use in enrichment and selective culture of Burkholderia spp. Those enrichment or selective culture media that demonstrate the greatest potential for use with different food matrices will be modified as needed to produce reliable media for enrichment and selective culture of Burkholderia spp. from food. Security Issues NOTE: THIS NOTICE WAS NOT POSTED TO FEDBIZOPPS.GOV ON THE DATE INDICATED IN THE NOTICE ITSELF (30-MAY-2003). IT ACTUALLY APPEARED OR REAPPEARED ON THE FEDBIZOPPS SYSTEM ON 23-FEB-2004. PLEASE CONTACT fbo.support@gsa.gov REGARDING THIS ISSUE.
- Web Link
-
Link to FedBizOpps document.
(http://www.eps.gov/spg/HHS/FDA/DCASC/223-03-2487/listing.html)
- Record
- SN00528422-F 20040225/040223224257 (fbodaily.com)
- Source
-
FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)
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