Loren Data's SAM Daily™

FBO DAILY ISSUE OF AUGUST 12, 2004 FBO #0990
SOLICITATION NOTICE

A -- Enantiomer Selectivity in Toxicity of Vinclozolin to Medaka Fish

Notice Date

8/10/2004
 

Notice Type

Solicitation Notice
 

NAICS

541380 — Testing Laboratories
 

Contracting Office

Environmental Protection Agency, Office of Research and Development, Ecosystems Research Division (LAB), 960 College Station Rd., Athens, GA, 30605
 

ZIP Code

30605
 

Solicitation Number

PMB4322
 

Response Due

8/25/2004
 

Archive Date

9/9/2004
 

Point of Contact

Beverly Owensby, Procurement Point of Contact, Phone 706-355-8010, Fax 706-355-8026,
 

E-Mail Address

Owensby.Anne@epa.gov
 

Description

The U.S. Environmental Protection Agency (EPA), Ecosystems Research Division (ERD) intends to award a competitive fixed-price purchase order using Federal Acquisition Regulation Part 13, Simplified Acquisition Procedures, for Enantiomer Selectivity in Toxicity of vinclozolin to Japanese Medaka Fish. Endocrine disrupting chemicals have the potential to adversely impact reproductive processes. Many environmental pesticides are known to possess endocrine disrupting properties. The dicarboxyimide fungicide vinclozolin has been shown to induce cytochrome P450 in both mice and rat mammalian systems. The monooxygenase enzymes are responsible for the hydrolysis of the parent vinclozolin and the known end-products have been shown to possess antiandrogenic properties in both mammals and fish. Vinclozolin is a chiral compound; that it, it consists of two species called enantiomers, mirror image isomers that usually differ in their fate and effects. The purpose of this acquisition is to test the enantiomers of various pesticides for differences in their toxic properties. Under this effort, a species of fish, the Japanese Medaka, will be employed in a new approach to assay the two separate enantiomers of vinclozolin for differences related to the induction of cytochrome P450 enzymes. The NAICS code for this procurement is 541380. A REQUEST FOR QUOTATION (RFQ) WILL BE AVAILABLE ON OR ABOUT AUGUST 25, 2004. Interested parties should send an email request for a copy of the RFQ to Owensby.Anne@epa.gov. RFQs and any subsequent amendments will be emailed to all interested parties. The RFQ will include the Statement of Work and the technical evaluation criteria under which offers will be evaluated. All questions should be directed to Anne Owensby via the email address above.
 

Place of Performance

Address: 960 College Station Rd., Athens, GA

Zip Code: 30605

Country: USA
 

Record

SN00640892-W 20040812/040810212859 (fbodaily.com)
 

Source

FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)

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