SOLICITATION NOTICE
R -- Professional, Adminstrative and Management Support Services
- Notice Date
- 9/14/2004
- Notice Type
- Solicitation Notice
- NAICS
- 541710
— Research and Development in the Physical, Engineering, and Life Sciences
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Allergy & Infectious Diseases/AMOB, 10401 Fernwood Drive, Suite 2NE70, MSC 4811, Bethesda, MD, 20817
- ZIP Code
- 20817
- Solicitation Number
- NOI4109
- Response Due
- 9/24/2004
- Archive Date
- 10/9/2004
- Description
- 17. This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are not being requested and a written solicitation will not be issued. The solicitation number for this acquisition is NOI4109 and is being issued as a Notice of Intent (NOI). The incorporated provisions and clauses are those in effect through Federal Acquisition Circular 01-24. The associated North American Industry Classification System (NAICS) Code 541710, which has a size standard of 500. National Institutes of Health (NIH) intends to procure vector salivary vaccine. This requirement is to continue a collaborative research study on Leishmania between NIH and developmental services from Centro de Pesquisa Goncalo Moniz, Fundacao Oswaldo Cruz, Universidade Federal da Bahia, Salvador, Bahia, Brazil. NIH will purchase animals and contract services to perform experiments with dogs in endemic areas of Leishmaniasis. The main objective is to identify natural salivary antigens, vaccinate dogs with the identified molecules and expose these dogs to infected sand flies under natural conditions. We will test if the vaccine can reduce the incidence of visceral Leishmaniasis in dogs and consequently humans. The following detailed services are required: 1) purchase of the dogs and care of the animals which consist of the purchase of 150 dogs to be housed and cared for the period of 1 year; 2) Immunization of dogs with constructs of DNA derived from salivary proteins of Lu. longipalpis according to approved animal protocol; 3) Measurements of Immune response of dogs against salivary proteins; A) DTH in dogs to verify DTH reaction against salivary proteins; B) Reverse transcription PCR analysis; C) Antibody levels against salivary proteins from Lutzomyia longipalpis with anti-sand fly saliva serologic test Elisa will be performed; 3) Testing salivary vaccines candidates in dogs which will be immunized with cDNA vaccine or with non recombinant plasmids; 4) Determine the transmissibility of L. chagasi from immunized dogs to uninfected sand flies; A) Aspirative biopsies from the spleen; B) Xeondiagnosis, dogs will be placed into individual cages sheated in sand fly netting; 11) And other related tasks an testing as required by project officer. This service is to begin September 27, 2004 thru October 1, 2005. The government will award a fixed price purchase order to the responsible contractor. The following FAR provisions and clauses apply to this acquisition: FAR 52.212-1 Instructions to Offerors Commercial Items; FAR 52.212.3 Offeror Representations and Certifications Commercial Items; FAR 52.212-4 Contractor Terms and Conditions Commercial Items; FAR 52.212-5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders Commercial Items. A completed copy of provisions at FAR 52.212-3 Offerors Representations and Certifications Commercial Items must be included. Copies of the aforementioned clauses are available upon request by telephone to Ms. Tonia Alexander at (301) 496-2607. Offerors must include with their offer a completed copy of the provisions at FAR 52.212-3, Offerors Representations and Certifications ? Commercial Items. Offers must be submitted no later than 5:00 PM Eastern Daylight Time (EDT) September 24, 2004 to Tonia Alexander. For delivery through the Postal Service, the address is NIH/NIAID/AMOB, 10401 Fernwood Road, Suite 2NE70, Room/2NE62C, MSC/4812, Bethesda, Maryland 20817-4812. Electronic submission will not be accepted. Requests for information concerning this requirement are to be addressed to Ms. Tonia Alexander (301) 496-2607. Collect calls will not be accepted. All responsible sources may submit an offer that will be considered by this agency. By submission of an offer, the offeror acknowledges the requirement that a prospective awardee shall be registered in the CCR database prior to award, during performance, and through final payment of any contract, basic agreement, basic ordering agreement, or blanket purchasing agreement resulting from this solicitation. Registration is available via the Internet at www.CCR.gov.
- Place of Performance
- Address: Salvador, Bahia
- Country: Brazil
- Country: Brazil
- Record
- SN00672724-W 20040916/040914211805 (fbodaily.com)
- Source
-
FedBizOpps.gov Link to This Notice
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