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FBO DAILY ISSUE OF APRIL 28, 2005 FBO #1249
SOLICITATION NOTICE

66 -- Axon Genepix 4000B Microarray Scanner

Notice Date

4/26/2005
 

Notice Type

Solicitation Notice
 

NAICS

334516 — Analytical Laboratory Instrument Manufacturing
 

Contracting Office

Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Research Contracts Br., 6120 Executive Blvd. EPS Suite 600, Rockville, MD, 20852
 

ZIP Code

20852
 

Solicitation Number

RFQ-NCI-50041-NG
 

Response Due

5/4/2005
 

Archive Date

5/19/2005
 

Description

The National Cancer Institute (NCI), Center for Cancer Research (CCR), plans to procure an Axon Genepix 4000B Microarray Scanner or equal. This acquisition will be conducted under the procedures for acquiring commercial items authorized in FAR Part 12 as the authority to use simplified procedures for commercial requirements provided in FAR Part 13.5. The North American Industry Classification System Code is 334516 and the business size standard is 500 employees. The following salient characteristics apply to the Genepix 4000B microarray scanner or equal: 1) Ability to scan standard microscope slides bearing in-house-printed microarrays or commercial microarrays, especially those from NimbleGen Biosystems, with non-confocal technology, 2) Ability to accurately and reproducibly scan at 10 micron or 5 micron resolution, to accommodate the above-mentioned arrays' formats, 3) Ability to scan two channels (laser excitation wavelengths of 532 and 635 nm) simultaneously and at high speed, 4) High dynamic range of detection, 5) Ability to acquire and save single or double-wavelength images of the array for analysis on NCI web-based software, 6) Must fit in a small footprint, not to exceed 16" Wide, 24" Long and 24" High, 7) Must come with software to run scanner, 8) Scanner software must enable on-the-fly feature visualization and histogram generation, for PMT optimization during scanning, and an option for automated PMT gain setting, 9) Machine software must be able to export color images in 24-bit JPEG format for analysis on NCI web-based software, 10) Microarray analysis software must be able to recognize features that are circular, square or irregular, with some flexibility for imperfect spotting, and to align the spots in terms of row, column and block, 11) Software must be able to import GAL files that identify the genes represented in all features, 12) Microarray analysis software must have user-defined manual as well as automatic flagging features for quality control and normalization and, 13) Microarray analysis software must have ability to visualize background pixels and to perform multiple methods of background subtraction. Justification: The Axon Genepix 4000B microarray scanner is required for the use of the NimbleGen arrays, which are being used in current studies, are very specialized in that the size of the oligonucleotide features (5 microns) are so small that only certain scanners have the resolution to allow acceptable imaging and quantification of the signals produced. The existing scanner currently used in house for microarray service core is the Axon Genepix 4000B along with NimbleGen arrays. Changing from NimbleGen microarrays will change the variables with already existing data and will interrupt correct interpretation of the studies being currently performed. Likewise changing to another scanner type will also affect study variables. Potential offerors may request a copy of the solicitation from Malinda Holdcraft via electronic mail at holdcram@exchange.nih.gov or via fax at 301-402-4513. If you have questions regarding this notice, they may be addressed to Malinda Holdcraft via electronic mail or fax. Estimated issue date of the solicitation is May 4, 2005 with an estimated due date of May 9, 2005. No collect calls will be accepted. In order to receive an award, contractor must be registered with the Central Contractor Registration (CCR) and Online Representations and Certifications Application (ORCA). Please reference this RFQ number on all correspondence, RFQ-NCI-50041-NG.
 

Place of Performance

Address: Bethesda, MD

Zip Code: 20892

Country: USA
 

Record

SN00795716-W 20050428/050426211813 (fbodaily.com)
 

Source

FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)

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