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FBO DAILY ISSUE OF APRIL 28, 2006 FBO #1614
SOLICITATION NOTICE

B -- Evaluation of Program entitled NHANES online analyst for dietary supplements (NOADS) and dietary supplement usage and total usual intakes of US children.

Notice Date
4/26/2006
 
Notice Type
Solicitation Notice
 
NAICS
541990 — All Other Professional, Scientific, and Technical Services
 
Contracting Office
Department of Health and Human Services, National Institutes of Health, Office of Administration, 6011 Executive Blvd, Rm 538, Rockville, MD, 20892-7663
 
ZIP Code
20892-7663
 
Solicitation Number
263-2006-Q-DT-0103
 
Response Due
5/5/2006
 
Archive Date
5/20/2006
 
Description
The National Institutes of Health intends to negotiate with the Research Triangle Institute, Research Triangle Park, NC for the development of a prototype for a web-enabled and real time analysis system for National Health and Nutrition Examination Survey (NHANES): The contractor shall provide but shall not be limited to the following services. 1. The contractor shall develop a format for obtaining evaluation input from nutritional scientists on the prototype for folate and vitamin B-12. 2. The contractor shall be responsible for application of the format at a scientific meeting of nutritionists. 3. The contractor shall provide a report of the evaluation findings and recommendations for improvements to meet potential user needs. 4. Shall provide a draft of publication quality manuscript with data tables and statistics generated by the final NOADS prototype illustrating the determination of total usual nutrient intakes from foods and supplements for folate and vitamin B-12 of US adults from NHANES 1999-2000 and 2001-2002. This draft manuscript shall also include percentile groupings for total usual folate and vitamin B-12 intakes with their respective nutrient status biomarkers. 5. Shall provide revised manuscript with modifications requested following Office of Dietary Supplements senior staff review and conference call between ODS and contractor. . There are two major tasks and eight deliverables for this project: Task A ? Shall provide special Data Analysis and data quality control (QC) tasks. 1. Shall provide data QC for specific nutrients calcium and fluoride. The contractor shall verify the location and availability of all intake data on calcium and fluoride from dietary supplements, food and all medications to insure the capture of all intakes of these nutrients. 2. Shall provide QC on data analyses. The contractor shall develop a separate analysis of basic supplement intake using those age groups used with previous publications to allow QC on the data analysis of these variables with previously published information on the same NHANES data sets. In addition, the contractor shall run a separate frequency distribution on the family income variable and recode each record with a new variable that reflects the frequency distribution break points. 3. The contractor shall reanalyze the data using the MEC weights to determine prevalence of supplement use. In addition, the contractor shall obtain a program that uses the CDC charts to identify how each child in the study samples BMI fell based upon age within the current scientifically acceptable weight categories of underweight, risk of underweight, probably a health weight, at risk of being, and overweight, validate the output on a subset of the data, then calculate and create a weight category variable for each child for analyses. 4. The contractor shall employ a step-wise introduction of those life style variables where the prevalence was statistically significant into an odds ratio model. 5. Shall develop an ingredient-based coding system for dietary supplements and prepare a summary for installation on the Office of Dietary Supplements web page. The contractor shall expand the explanatory text and development history of the ingredient-based dietary supplement coding system used in these studies into a self-explanatory text for posting on the ODS website. This site shall be available to the scientific community so that a unified classification system can be employed by investigators enhancing ability to compare data across studies. Task B shall provide Special Analysis steps for a manuscript on usual intake. 1. The contractor shall acquire and format the Continuing Survey of Food Intake by Individuals (CSFII) to use as second day recall for the Iowa method. Literature has demonstrated the importance of calculating the variability of intake in order to estimate usual intake. Since second recall data is not available for the NHANES datasets, the contractor shall obtain and appropriately program suitable data from the CSFII data to use as the second recall to estimate usual intake of food. 2. The contractor shall develop, discuss with ODS and calculate intake of nutrients from breast milk for all infants who consume breast milk; add this analysis into the usual intake model. Shall develop an algorithm to estimate the nutrient intake of these infants from breast milk, discuss it with ODS and then employ it using the Iowa method to calculate usual intake in these infants. 3. The contractor shall review all of its programming code, make it user friendly and provide instructions so other statisticians could employ the same code to do a comparison analysis of the data from both publications. The National Institutes of Health intends to negotiate with the Research Triangle Institute, Research Triangle Park, NC for the development of a prototype for a web-enabled and real time analysis system for National Health and Nutrition Examination Survey (NHANES): The contractor shall provide but shall not be limited to the following services. 1. The contractor shall develop a format for obtaining evaluation input from nutritional scientists on the prototype for folate and vitamin B-12. 2. The contractor shall be responsible for application of the format at a scientific meeting of nutritionists. 3. The contractor shall provide a report of the evaluation findings and recommendations for improvements to meet potential user needs. 4. Shall provide a draft of publication quality manuscript with data tables and statistics generated by the final NOADS prototype illustrating the determination of total usual nutrient intakes from foods and supplements for folate and vitamin B-12 of US adults from NHANES 1999-2000 and 2001-2002. This draft manuscript shall also include percentile groupings for total usual folate and vitamin B-12 intakes with their respective nutrient status biomarkers. 5. Shall provide revised manuscript with modifications requested following Office of Dietary Supplements senior staff review and conference call between ODS and contractor. . There are two major tasks and eight deliverables for this project: Task A ? Shall provide special Data Analysis and data quality control (QC) tasks. 1. Shall provide data QC for specific nutrients calcium and fluoride. The contractor shall verify the location and availability of all intake data on calcium and fluoride from dietary supplements, food and all medications to insure the capture of all intakes of these nutrients. 2. Shall provide QC on data analyses. The contractor shall develop a separate analysis of basic supplement intake using those age groups used with previous publications to allow QC on the data analysis of these variables with previously published information on the same NHANES data sets. In addition, the contractor shall run a separate frequency distribution on the family income variable and recode each record with a new variable that reflects the frequency distribution break points. 3. The contractor shall reanalyze the data using the MEC weights to determine prevalence of supplement use. In addition, the contractor shall obtain a program that uses the CDC charts to identify how each child in the study samples BMI fell based upon age within the current scientifically acceptable weight categories of underweight, risk of underweight, probably a health weight, at risk of being, and overweight, validate the output on a subset of the data, then calculate and create a weight category variable for each child for analyses. 4. The contractor shall employ a step-wise introduction of those life style variables where the prevalence was statistically significant into an odds ratio model. 5. Shall develop an ingredient-based coding system for dietary supplements and prepare a summary for installation on the Office of Dietary Supplements web page. The contractor shall expand the explanatory text and development history of the ingredient-based dietary supplement coding system used in these studies into a self-explanatory text for posting on the ODS website. This site shall be available to the scientific community so that a unified classification system can be employed by investigators enhancing ability to compare data across studies. Task B shall provide Special Analysis steps for a manuscript on usual intake. 1. The contractor shall acquire and format the Continuing Survey of Food Intake by Individuals (CSFII) to use as second day recall for the Iowa method. Literature has demonstrated the importance of calculating the variability of intake in order to estimate usual intake. Since second recall data is not available for the NHANES datasets, the contractor shall obtain and appropriately program suitable data from the CSFII data to use as the second recall to estimate usual intake of food. 2. The contractor shall develop, discuss with ODS and calculate intake of nutrients from breast milk for all infants who consume breast milk; add this analysis into the usual intake model. Shall develop an algorithm to estimate the nutrient intake of these infants from breast milk, discuss it with ODS and then employ it using the Iowa method to calculate usual intake in these infants. 3. The contractor shall review all of its programming code, make it user friendly and provide instructions so other statisticians could employ the same code to do a comparison analysis of the data from both publications. This proposed action is for services for which the Government intends to solicit and negotiate with only one source. Interested parties may identify their interest and capability to respond to the requirement or submit proposals. This notice of intent is not a request for competitive quotations. However, all quotes received within ten days after the date of publication of this synopsis will be considered by the Government . A determination by the Government not to compete this proposed simplified acquisition requirement based upon responses to this notice is solely within the discretion of the Government. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive acquisition.
 
Place of Performance
Address: 9000 Rockville Pike, Bethesda, MD
Zip Code: 20892
Country: USA
 
Record
SN01035436-W 20060428/060426220538 (fbodaily.com)
 
Source
FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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