SOLICITATION NOTICE
68 -- Multi-Analye COOH Microspheres
- Notice Date
- 7/14/2006
- Notice Type
- Solicitation Notice
- NAICS
- 325413
— In-Vitro Diagnostic Substance Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 6120 Executive Blvd. EPS Suite 600, Rockville, MD, 20852
- ZIP Code
- 20852
- Solicitation Number
- Reference-Number-NCI-60107-NV
- Response Due
- 7/24/2006
- Archive Date
- 8/8/2006
- Description
- The National Cancer Institute (NCI), Center for Cancer Research (CCR), Pediatric Oncology Branch (POB) plans to enter into a sole source procurement for Multi-Analye COOH Microspheres from Luminex Corporation, 12212 Technology Blvd., Austin, TX 78727. The North American Industry Classification System Code is 325413 and the business size standard is 500 employees. This acquisition will be processed under FAR Part 12 ? Acquisition for Commercial Items. Luminex is the only source known to the NCI researcher for these proprietary beads which will be used in their Government owned Luminex bead-based detection system (Luminex 100 IS) and are required for the continuation of ongoing experiments as detailed below in their JOFOC. However, if any interested party believes it can perform the requirement as detailed in the JOFOC they may submit a statement of capabilities. The statement of capabilities and any other furnished information must be in writing and must contain material in sufficient detail to allow the NCI researcher to determine if the party can perform this requirement. An original and one copy of the capability statement must be received in the contracting office by 1:00 pm EDT, on July 24, 2006. Faxed and emailed capability statements are NOT authorized. All questions must be in writing and may be emailed to Debbie Moore at dm170b@nih.gov or faxed (301) 402-4513. It is the vendor?s responsibility to call (301) 402-4509 and verify that questions were received. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award from the NCI contractors must be registered in the Online Representations and Certifications Applications (ORCA). Please refer to http://orca.bpn.gov in order to register. In addition, contractors must be registered in the Central Contractor Registration (CCR) www.ccr.gov. No collect calls will be accepted. JUSTIFICATION FOR OTHER THAN FULL AND OPEN COMPETITION Part I: Background information and Description of Acquisition Title: Multi-Analye COOH Microspheres Purpose/Brief History: Pediatric Oncology Branch of the National Cancer Institute is engaged in the study of discovery of miRNAs that play important roles in human neuroblastoma. From prior studies using microarray, miRNA expression was profiled in 100 neuroblastoma samples. In this project, the microarray results will be verified using quantitative method. Bead-based array has been used to detect miRNAs due to its capability of multiplex (up to 100) and flexibility. PART II: Facts and reasons to Justify Other than Full and Open Competition Statutory authority FAR 13.106-1(b)(1) b) Soliciting from a single source. (1) For purchases not exceeding the simplified acquisition threshold, contracting officers may solicit from one source if the contracting officer determines that the circumstances of the contract action deem only one source reasonably available (e.g., urgency, exclusive licensing agreements, or industrial mobilization). Justification: Luminex beads are proprietary 100 distinct color-coded microspheres designed and manufactured by Luminex Corporation for their bead-based detection systems (e.g. Luminex 100 IS). The beads are covered with reactive functional groups (in this case ?COOH) for attaching various capture biological molecules including DNA oligos. The major advantages of these beads are: 1) The hybridization reaction is completed faster (15 min to 1 hour) than the conventional slide-based microarray techniques (~16 hours). 2) Bead-based hybridization results in more reproducible data than the slide-based method. 3) The platform is very flexible to adding novel target genes. 4) The assay is quantitative rather than qualitative compared to the conventional microarray. 5) 100 distinct color-coded beads give this system multiplexibility compared to qPCR method. Luminex Corporation is the only manufacturer of these proprietary beads. Luminex beads have been in the market since 1995 and have been successfully used in SNP geno-typing, gene expression and protein detection methods. We already have acquired the detection system, Luminex 100 IS, and have been testing the beads on the instrument. The Luminex system fulfills the quantization needs for specific RNAs in biological samples in a high-throughput fashion. Since the Government has been testing a few Luminex beads for pilot studies successfully, it plans to continue its ongoing project in an expended scale using the full capacity of 100 Luminex beads.
- Record
- SN01089208-W 20060716/060714220548 (fbodaily.com)
- Source
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