SOLICITATION NOTICE
B -- Marinobufufagenin as a target for DIGIBIND in preeclampsia
- Notice Date
- 5/25/2007
- Notice Type
- Solicitation Notice
- NAICS
- 541990
— All Other Professional, Scientific, and Technical Services
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Aging, 5600 Nathan Shock Drive, Baltimore, MD, 21224, UNITED STATES
- ZIP Code
- 00000
- Solicitation Number
- LCS1254
- Response Due
- 5/30/2007
- Archive Date
- 6/14/2007
- Description
- The National Institute on Aging, IRP, intends to negotiate and award a purchase order on a noncompetitive basis with the University of Toledo, 3000 Arlington Avenue, Toledo, OH 43614 for a project entitled ?Marinobufagenin as a target for DIGIBIND in preeclampsia?. The vendor will aim to demonstrate that in hypertensive patients with ESRD, DIGIBIND, due to blockade of MBG, lowers blood pressure and reduces systemic oxidant stress. This trial will provide basis for the development of a ?clinically-usable? anti-MBG antibody. Specific aims of the study are: 1) to quantify changes in the levels of blood pressure following 2 weeks of one-a-week administration of three does of DIGIBIND (0.1mg/kg; 0.4 mg/kg, and 1.6 mg/kg); 2) to quantify changes in the leels of blood pressure following 2 weeks of once-a-week administration of three doses of DIGIBIND (0.1mg/kg; 0.4 mg/kg; and 1.6mg/kg). Only one responsible source and no other supplies or services will satisfy agency requirements, 41 U.S.C. 253 (c) (1), FAR 6.302-1 (b) (1). The cited authority is applicable because the University of Toledo is the only source that can fulfill the requirements of this contract after a market search was performed. The period of performance is 12 months. The North American Industry Classification (NAICS) is 541990 and the size standard is $6.5 million. This acquisition is being conducted under Simplified Acquisition procedures and is exempt for the requirements of FAR, Part 6, Competition Requirement.
- Place of Performance
- Address: Toledo, OH
- Zip Code: 43614
- Country: UNITED STATES
- Zip Code: 43614
- Record
- SN01303349-W 20070527/070525220524 (fbodaily.com)
- Source
-
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