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FBO DAILY ISSUE OF DECEMBER 04, 2008 FBO #2565
SOURCES SOUGHT

A -- NHLBI Proteomic Centers

Notice Date
12/2/2008
 
Notice Type
Sources Sought
 
NAICS
541712 — Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
 
Contracting Office
Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
 
ZIP Code
20892-7902
 
Solicitation Number
NHLBI-HV-10-05
 
Response Due
12/17/2008
 
Archive Date
1/15/2009
 
Point of Contact
Michelle Kouis,, Phone: (301) 435-0340, Joanne F Deshler,, Phone: (301) 435-0340
 
E-Mail Address
kouisma@nhlbi.nih.gov, deshlerj@nhlbi.nih.gov
 
Small Business Set-Aside
N/A
 
Description
This Sources Sought Notice is for information and planning purposes only and shall not be construed as a solicitation or as an obligation on the part of the National Heart, Lung, and Blood Institute (NHLBI). The purpose of this Sources Sought Notice is to identify qualified small business concerns [including Small Disadvantaged Businesses (SDB), Woman-Owned Small Businesses (WOSB), Historically Underutilized Business Zone (HUBZone) Small Businesses, Veteran-Owned Small Businesses (VOSB) and Service-Disabled Veteran-Owned Small Businesses (SDVOSB)] that are interested in and capable of performing the work described herein. The NHLBI does not intend to award a contract on the basis of responses nor otherwise pay for the preparation of any information submitted. As a result of this Sources Sought Notice, the NHLBI may issue a Request for Proposal (RFP). THERE IS NO SOLICITATION AVAILABLE AT THIS TIME. However, should such a requirement materialize, no basis for claims against NHLBI shall arise as a result of a response to this Sources Sought Notice or the NHLBI’s use of such information as either part of our evaluation process or in developing specifications for any subsequent requirement. The NHLBI is seeking capability statements from all eligible and qualified small business concerns under the North American Industry Classification System (NAICS) code 541712 with a size standard of 500 employees. Based on the responses received from this Sources Sought Notice, the proposed acquisition may be solicited as a Total Small Business Set-Aside. The NHLBI Proteomics Center contractors will integrate expertise in multiple disciplines (proteomics, physiologists, clinicians, molecular biologist, genomics, chemistry, physics, engineering, computational biology, bioinformatics, and biostatistics) to advance proteomic applications in heart, lung, blood, and sleep diseases and disorders. NHLBI Proteomic Center contractors will address a specific clinical need/problem/disease/ process using three approaches: 1) proteomic technology development; 2) mechanistic and functional understanding of the proteome, its interactions and dynamics and 3) clinical application of proteomic approaches and discoveries. The Proteomic Center interactive team will work on addressing a common physiological/pathophysiological need/problem/disease. The components should be interdependent and drive each other’s science and progress. Specifically, Proteomic Centers will be expected to enhance proteomic tools and technologies with the goal of using them for mechanistic and functional understanding of HLBS diseases and disorders. Enhancement of proteomic tools and technologies can include hardware or software to improve the measurement, characterization, or comparison of proteins, peptides, PTMs, isoforms, genomic/epigenomic tags, small molecules, or other related cellular or tissue components. Mechanistic and functional understanding can include, but is not limited to, experimental and/or computational approaches to molecular function/dysfunction, dynamics, interactions, pathways, process, transport, or other related actions, in cells, tissues, organs, and whole organisms. The Centers should also work with an eye toward clinical studies using the proteomic tools, technologies, mechanisms, and functional understanding to guide human subject studies. It is expected that all Centers will have human research studies during the course of the project period. The Centers should leverage existing resources to support these human subject studies, such as CTSA, Clinical Networks, ongoing Clinical Trials, ongoing Cohort studies, and industry supported studies. The NHLBI Proteomic Centers will be proposals at the cutting edge of science. Thus, it is important that the funded Centers interact to share information on technical objectives, progress and impediments, as well as exchange ideas, and, where appropriate, establish collaborations. All research products and results must be made available to the research community in a timely fashion. Each Center must have a project plan that addresses milestones, deliverables, and sharing; including software, technology, biological data, and resources. The NHLBI Proteomic Center Investigators must have documented training, experience, expertise, and availability to implement the goals of this program. The organizational and administrative structure, and the adequacy of the facilities and resources necessary to meet the objective of the proposed Proteomics Center (including institutional commitment to the Center), must be demonstrated. Interested qualified small business organizations should submit a tailored capability statement for this requirement, not to exceed 10 single-sided pages (including all attachments, resumes, charts, etc.) presented in single-space and using a 12-point font size minimum, that clearly details the ability to perform the aspects of the Sources Sought Notice described above. All proprietary information should be marked as such. Statements should also include an indication of current certified small business status; this indication should be clearly marked on the first page of your capability statement (preferably placed under the eligible small business concern’s name and address). Responses will be reviewed only by NIH personnel and will be held in a confidential manner.
 
Web Link
FedBizOpps Complete View
(https://www.fbo.gov/?s=opportunity&mode=form&id=ec4f804783496d837a377fc17357d63d&tab=core&_cview=1)
 
Record
SN01712220-W 20081204/081202215223-ec4f804783496d837a377fc17357d63d (fbodaily.com)
 
Source
FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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