SOURCES SOUGHT
Q -- Professional Services in Support of Cleft Lip Palate Study
- Notice Date
- 3/15/2011
- Notice Type
- Sources Sought
- NAICS
- 621111
— Offices of Physicians (except Mental Health Specialists)
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
- ZIP Code
- 20892-7902
- Solicitation Number
- NHLBI-CSB-(HG)-2011-125-DLM
- Archive Date
- 4/6/2011
- Point of Contact
- Dorothy Maxwell, Phone: 301-435-0352
- E-Mail Address
-
maxwelld@mail.nih.gov
(maxwelld@mail.nih.gov)
- Small Business Set-Aside
- Total Small Business
- Description
- This Sources Sought Notice (SS) is for information and planning purposes only and shall not be construed as a solicitation or as an obligation on the part of the National Heart, Lung, and Blood Institute (NHLBI). The purpose of this SS is to identify qualified small business concerns [including Small Disadvantaged Businesses (SDB), Woman-owned Small Businesses (WOSB), Historically Underutilized Business Zone (HUBZone) Small Businesses, Veteran-Owned Small Businesses (VOSB) and Service-Disabled Veteran-owned Small Businesses (SDVOSB] that are interested in and capable of providing Professional Services in support of a Cleft Lip Palate study for Syrian Arab Republic families. The NHLBI does not intend to award a contract on the basis of responses nor otherwise pay for the preparation of any information submitted. As a result of this Sources Sought notice, the NHLBI may issue a Request for Quote (RFQ). THERE IS NO SOLICITATION AVAILABLE AT THIS TIME. However, should such a requirement materialize, no basis for claims against NHLBI shall arise as a result of a response to this Sources Sought notice or the NHLBI’s use of such information as either part of our evaluation process or in developing specifications for any subsequent requirement. The NHLBI is seeking capability statements from all eligible small business concerns [particularly Small Disadvantaged Businesses (SDB), Woman-owned Small Businesses (WOSB), Historically Underutilized Business Zone (HUBZONE) Small Businesses, Veteran-Owned Small Businesses (VOSB) and Service-Disabled Veteran-owned Small Businesses (SDVOSB)] under the North American Industry Classification System (NAICS) code 621111 with a size standard of $10.0M Per Annum. Based on the responses received from this SOURCES SOUGHT announcement, the proposed acquisition may be solicited as a Total Small Business Set-Aside. All eligible small business concerns responding to this Sources Sought Announcement must have the capabilities to provide the below services within 30 days after receipt of purchase order. This contract covers work to be performed as part of a continued collaborative effort under protocol OH97-HG-N035 (most recently approved by the NHGRI Institutional Review Board on June 23, 2010). The National Human Genome Research Institute (NHGRI), NIH is conducting a study of the inherited susceptibility to oral clefts, with emphasis on non-syndromic oral clefts. The objective of the study is to identify the gene(s) involved in heritable oral clefts by linkage analysis, association analysis and gene mapping strategies. Characterization of genes involved in causing inherited oral clefts could provide important insight into the inheritance and pathogenesis of this disease. As such, clinical data, family history data and blood samples from individuals in large families with multiple individuals affected with oral clefts is needed. Large families with multiple living affected family members are rare in the United States, given today’s small average sibship size, and thus it is important to obtain data on such families from countries where such families are more common. In the Syrian Arab Republic, family sizes are large and intergeneration times are much shorter than in the U.S. These services are needed since it would not be feasible, either logistically or financially, to bring the members of the participating families to the U.S to be seen at the NIH and investigators at the NIH have no way to identify families with multiple affected individuals who reside in the Syrian Arab Republic. A contract with a local clinician who has proven that he can enroll suitable families is the most efficient and most economical way to conduct this study. STATEMENT OF WORK The purpose of this procurement is to provide professional services to the researchers dedicated to the study. These services will be in the areas of: determination of eligibility, patient registration, clinical evaluation of family members, biological sample collection and shipment, recontact of previously studied family members as needed by the NIH scientists to update information or consents and to explain clinically relevant results if needed. The objective of the study is to identify the gene(s) involved in heritable oral clefts by linkage analysis and gene mapping strategies. Characterization of genes involved in causing inherited oral clefts could provide important insight into the inheritance and pathogenesis of this disease. CONTRACTOR REQUIREMENTS: The contractor will engage in several activities, including: (1) determination of eligibility, (2) patient registration, (3) clinical evaluation of family members, (4) biological sample collection and shipment, and (5) recontact of previously studied family members as needed by the NIH scientists for updating information, obtaining additional informed consent, and communicating results to families when approved by both the NIH and Syrian ethics oversight committees. REPORTING REQUIREMENTS AND DELIVERABLES: The contractor will work with the research team and other members of the NHGRI on a weekly basis. They will communicate progress and provide summary of activities, either orally or in writing, to Principal Investigator on a quarterly basis. In addition to the quarterly progress report, the contractor will deliver the pedigree data and biological specimens as collection of each family is completed. The contractor will meet the principal investigator at a scientific meeting as needed for planning and development of the data collection efforts. PERIOD OF PERFORMANCE AND LEVEL OF EFFORT: The overall estimated period of performance for the contract will be twelve months. PROGRAM MANAGEMENT AND CONTROL REQUIREMENTS: The contractor will work independently with no direct supervision by any government employee. The study Principal Investigator and other research team members will provide guidance in terms of technical reporting needs and study requirements of the project supported. GOVERNMENT RESPONSIBILITIES: The contractor will provide his own supplies, computer equipment, and space to work. On occasions when collaborative efforts will occur, the contractor will have temporary use of government space and computer equipment on an as-needed basis. Interested parties are expected to review this notice to familiarize yourself with the requirements of this project; failure to do so will be at your firm’s own risk. Interested parties should submit a tailored capability statement for this requirement, not to exceed 20 single-sided pages (including all attachments, resumes, charts, etc.) presented in single-space and using a 12-point font size minimum, that clearly details the ability to perform the aspects of the notice described above and in the attached draft statement of work. All proprietary information should be marked as such. Statements should also include an indication of current certified small business status; this indication should be clearly marked on the first page of your capability statement (preferably placed under the eligible small business concern’s name and address). Responses will be reviewed only by NIH personnel and will be held in a confidential manner. All capability Statements sent in response to this SOURCES SOUGHT notice must be submitted electronically (via email) to Dorothy Maxwell, Contract Specialist, at maxwelld@mail.nih.gov in either MS Word or Adobe Portable Document Format (PDF), March 22, 2011, 7:30 AM, EST. All responses must be received by the specified due date and time in order to be considered.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NHLBI/NHLBI-CSB-(HG)-2011-125-DLM/listing.html)
- Place of Performance
- Address: NIH, Bethesda, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN02401532-W 20110317/110315235241-a0732ee01e00a0cf8a9f9a11a57d4e06 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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