SOLICITATION NOTICE
66 -- BioView Duet-3 Automated Scanner–Microscope with 50-Slide Loader
- Notice Date
- 9/2/2011
- Notice Type
- Presolicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 6120 Executive Blvd., EPS Suite 600, Rockville, Maryland, 20852
- ZIP Code
- 20852
- Solicitation Number
- NCI-110181-TG
- Archive Date
- 9/27/2011
- Point of Contact
- Terry Galloway, Phone: 301-402-4509, Caren N Rasmussen, Phone: (301) 402-4509
- E-Mail Address
-
gallowaytl@mail.nih.gov, cr214i@nih.gov
(gallowaytl@mail.nih.gov, cr214i@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Contracting Office Address Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 6120 Executive Blvd. EPS Room 6074, Rockville, MD, 20852, UNITED STATES Description The National Cancer Institute (NCI), Center for Cancer Research (CCR), Laboratory of Pathology plans to procure on a sole source basis the brand name BioView Duet-3 Automated Scanner-Microscope with 50-Slide Loader and Integrated Barcode Reader from BioView USA Inc., 44 Manning Road, Billerica, MA 01821. This acquisition will be processed under the procedures for FAR Part 12 - Acquisition for Commercial Items and will be made pursuant to the authority in FAR 13.106-1(b)(2) and 13.501-(a)(1) using simplified acquisition procedures for commercial acquisitions. The North American Industry Classification System code is 334516 and the business size standard is 500 employees. Only one award will be made as a result of this solicitation. This will be awarded as a firm fixed price type contract. The delivery date shall be ninety (90) days from date of award. The Chromosome Pathology Unit (CPU) in the Laboratory of Pathology performs Fluorescence In Situ Hybridization (FISH) assays on formalin-fixed paraffin-embedded tissues to support clinical trials at the NCI and NIH. The demand for this testing is high; the CPU receives orders for FISH tests on clinical tumor samples daily, and currently supports 15 clinical trials at the NIH. The active test menu includes four FISH assays for clinically significant chromosomal translocations and amplification events. In addition, the CPU is currently developing and validating sixteen new FISH tests for additional frequent chromosomal abnormalities in cancers that have been requested by NCI investigators. With the growing FISH testing menu, CPU anticipates a steady increase in workload, and estimates a 4- to 6-fold increase in FISH test requests. An important solution to expand the capabilities for clinical FISH services is to acquire an automated FISH scanner system. The following salient characteristics identified by the CPU as necessary apply to the BioView Duet-3 Automated Scanner-Microscope with 50-Slide Loader from BioView USA: • The instrument shall be of a compact design (desktop) and separate review workstation with touch sensitive monitor, mouse pen and vertical or horizontal positioned computer monitor, which can be placed in remote location. Hardware and Software requirements: • The System must utilize 40x oil objectives for FISH image scanning in multiple focal planes. • The System must use a minimum four megapixel CCD Chip for wider fields of view scanning and higher scanning speed while maintaining high image resolution with the advantage of shorter scanning times and higher throughput. • The System must provide an independent review station (with touch screen monitor) where the analysis software must provide an "Analysis Window" where the User can scroll through the focal planes of each target image either through each of the single filters or through the combined image. • The System must have the ability to automatically match the target areas of two tissue sections, the first being stained with brightfield stains and the second, consequent section, being tagged with fluorescent markers including immunofluorescent antibody or FISH probes. When second (fluorescent) slides are utilized the images should be matched automatically to the corresponding coordinates at the individual cell level. • Target FISH using Brightfield Morphological Classification Application: The System must provide the option to add the capabilities of a "Target FISH application" which includes brightfield optics and scanning software. With brightfield stains such as H&E and PAP, cells captured in brightfield are classified based on their morphological characteristics. After subsequent hybridization with selected probes, the "targeted" specific class of cells must be located and the FISH signal pattern must be reported for each individual cell in that class. • The application must provide automatic light exposure adjustment to eliminate interference in signal pattern reading from the nonspecific fluorescence binding. The automatic exposure will be adjusted and optimized only for those signals within the borders of the DAPI stained nucleus. • The application must be able to analyze FISH probes in core biopsies that are in the form of Tissue MicroArrays (TMA) with the additional ability to recognize and label each core as a separate specimen and provide the FISH report using the Touch Screen Review Station and the image editing tools provided. • The application must be able to accommodate all probe families (enumeration, break-apart, amplification) and all probe manufacturers including customized and in house preparations and cocktails and be capable to analyze multiple FDA cleared probes. The 40x oil objective, which is required for our work for automated tissue scanning, is only offered in the Bioview Duet 3. The 40x oil objective for scanning allows for faster acquisition and processing, and the images are of a higher quality as compared to 40x dry objectives. Additionally, the instrument is supplied with a metal halide light source which allows for extended lamp life, and the Duet 3 is the only known system that allows automatic scanning, recognizing, and labeling of individual cores of TMA slides. This notice is not a request for a competitive quotation. However, if any interested party believes it can meet the above requirement, it may submit a statement of capabilities. The statement of capabilities and any other information furnished must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can perform the requirement. Capability statements must be received in the contracting office by 11:00 AM EST, on September 12, 2011. For further information, please contact Terry Galloway, Contract Specialist via electronic mail at gallowaytl@mail.nih.gov. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. No collect calls will be accepted. No faxed or emailed capability statements will be accepted. In order to receive an award, contractors must be registered and have valid certification in the Central Contractor Registration (CCR) and the Online Representations and Certifications Applications (ORCA). Reference: NCI-110181-TG on all correspondence.
- Web Link
-
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- Record
- SN02562513-W 20110904/110903000440-c49896f9d03762b23f974cf92a208860 (fbodaily.com)
- Source
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