MODIFICATION
A -- NONHUMAN PRIMATE CORE FUNCTIONAL GENOMICS LABORATORY FOR AIDS VACCINE RESEARCH AND DEVELOPMENT
- Notice Date
- 6/8/2012
- Notice Type
- Modification/Amendment
- NAICS
- 541712
— Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Office of Acquisitions, 6700 B Rockledge Room 3214 MSC7612, Bethesda, Maryland, 20892-7612
- ZIP Code
- 20892-7612
- Solicitation Number
- RFP-NIAID-DAIDS-NIHAI2012142
- Archive Date
- 9/27/2012
- Point of Contact
- Robert J. Corno, Phone: 3014513691, John Manouelian, Phone: 301-496-0612
- E-Mail Address
-
robert.corno@nih.gov, manouelj@mail.nih.gov
(robert.corno@nih.gov, manouelj@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- The purpose of this modification is to revise the "Description" field of the Pre-Solicitation announcement to incorporate a brief description of the Electronic Contract Proposal Submission (eCPS) website requirements that are applicable to this solicitation: The NIAID provides immunological and virological support for nonhuman primate (NHP) conducted at NIAID's Simian Vaccine Evaluation Unit (SVEU) contract sites and by DIADS-supported vaccine researchers through three existing NHP Core Laboratories (NHP Core Labs): the Humoral Immunology Core Lab, the Cellular Immunology Core Lab, and the Viral Ribonucleic Acid (RNA) Core Lab. The Functional Genomics NHP Core Laboratory will thus become a fourth NHP Core Lab. The objective of the Core Laboratories has been to insure standardization and comparability of functional genomics services and assays conducted for these SVEU and DAIDS-supported preclinical NHP studies. The purpose of the proposed contract will be to provide support for a Functional Genomics NHP Core Laboratory for the conduct and improvement of assays designed to generate specific quantitative genomic expression profiles and network diagrams from RNA samples obtained from NHPs enrolled in priority SVEU protocols and DAIDS-supported investigator-initiated NHP studies. The Contractor shall compile and analyze the generated data using bioinformatics and biocomputing tools (e.g., unbiased hierarchical clustering methods, sophisticated network algorithms, etc.) with the intent of identifying gene signatures that could potentially define correlates of protection and predict vaccine efficacy. It is anticipated that one cost reimbursement, term type contract will be awarded for a 1-year Base period plus four 1-year options for a possible total period of performance of 5 years beginning on or about June 17, 2013. The performance requirement will be for the delivery of 3.85 full time equivalents (FTEs) per year for the base period (Year 1) and option periods (Years 2 through 5), which may be unilaterally exercised by the Government. In addition, the Government may unilaterally exercise options to accommodate significant increases in work to be provided for the base period and option periods. Should the Government elect to exercise these options, the Contractor shall provide resources for the unanticipated increase in work volume by.95 FTE for each option exercised. The Government may exercise an option up to two times in any year of the contract. For this solicitation, the NIAID requires proposals to be submitted in three methods: (1) Paper, (2) Disc (CD or DVD), and (3) Online via the NIAID Electronic Contract Proposal Submission (eCPS) website. The content of the paper, disc, and online proposals must be identical. Submission of proposals by facsimile or e-mail is not acceptable. For directions on using eCPS, go to the website https://ecps.niaid.nih.gov and then click on "How to Submit." To submit online using eCPS, offerors must have a valid NIH electronic Research Administration (eRA) Commons account, which provides authentication and serves as a vehicle for secure transmission of documents and communication with the NIAID. The eRA Commons registration process may take up to 4 weeks. For more information, please see http://era.nih.gov/applicants/how-to_steps.cfm#register. Any responsible offeror may submit a proposal which will be considered by the Agency. This RFP will be available electronically on/about May 14, 2012, and may be accessed through FedBizOpps http://www.fedbizopps.gov/. This notice does not commit the Government to award a contract. No collect calls will be accepted. No facsimile transmissions will be accepted.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIAID/RFP-NIAID-DAIDS-NIHAI2012142/listing.html)
- Record
- SN02770707-W 20120610/120608235353-8839e26e49acda14aec73cdb895c9661 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
| FSG Index | This Issue's Index | Today's FBO Daily Index Page |