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FBO DAILY ISSUE OF JUNE 20, 2012 FBO #3861
SOURCES SOUGHT

66 -- Microscale Thermophoresis Instruments

Notice Date
6/18/2012
 
Notice Type
Sources Sought
 
NAICS
333314 — Optical Instrument and Lens Manufacturing
 
Contracting Office
Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
 
ZIP Code
20892-7902
 
Solicitation Number
NHLBI-CSB-(TR)-2012-175-RSF
 
Archive Date
7/12/2012
 
Point of Contact
Rashida S. Ferebee, Phone: 3014352605
 
E-Mail Address
ferebeers@nhlbi.nih.gov
(ferebeers@nhlbi.nih.gov)
 
Small Business Set-Aside
N/A
 
Description
This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of all business sources; (2) the availability and capability of all business sources of qualified small business sources; (3) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (4) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. The NHLBI does not intend to award a contract on the basis of responses nor otherwise pay for the preparation of any information submitted. As a result of this SBSS notice, the NHLBI may issue a Request for Quote (RFQ). THERE IS NO SOLICITATION AVAILABLE AT THIS TIME. However, should such a requirement materialize, no basis for claims against NHLBI shall arise as a result of a response to this Sources Sought notice or the NHLBI's use of such information as either part of our evaluation process or in developing specifications for any subsequent requirement. The NHLBI is seeking capability statements from all eligible business concerns [particularly Small Disadvantaged Businesses (SDB), Woman-owned Small Businesses (WOSB), Historically Underutilized Business Zone (HUBZone) Small Businesses, Veteran-Owned Small Businesses (VOSB) and Service-Disabled Veteran-owned Small Businesses (SDVOSB)] under the North American Industry Classification System (NAICS) code 333314 with a size standard of 500 Employees. Based on the responses received from this SOURCES SOUGHT announcement, the proposed acquisition may be solicited as a Total Small Business Set-Aside. All eligible small business concerns responding to this Sources Sought Announcement must have the capabilities to provide the below services upon receipt of order. Interested parties are expected to review this notice to familiarize yourself with the requirements of this project; failure to do so will be at your firm's own risk. MISSION/PURPOSE: The mission of the Probe Development Branch is to apply the tools of small molecule screening and discovery to the development of chemical probe research tools, for use in the study of protein and cell functions, and biological processes relevant to physiology and disease. Probe Development will optimize biochemical, cellular and model organism-based assays submitted by the biomedical research community; perform automated high-throughput screening (HTS); and perform chemistry optimization on confirmed hits to produce chemical probes for dissemination to the research community. The Probe Development Branch, part of the National Center for Advancing Translational Sciences, NCATS requires an assay technology platform that supports biophysical characterization of hit compounds that are of interest with putative protein targets. Among existing technologies, microscale thermophoresis (MST) has recently emerged as a cutting edge platform which utilized a physics principle for the first time for biomolecular interaction studies. PRODUCT/SERVICE DESCRIPTION: The Microscale Thermophoresis Instrument shall meet the following requirements: 1. Instrument to measure Microscale Thermophoresis (MST) of molecules 2. Must measure tryptophane fluorescence 3. Must use an IR laser to create a microscopic temperature gradient 4. Must use capillaries as a sample format 5. Must be able to measure interactions of biomolecules in free solution 6. Must be able to measure label-free 7. Must be temperature controlled 25-45 Celsius 8. Must be able to control the IR-Laser induced Temperature gradient 9. Must be able to measure Thermophoresis of up to 16 samples in one run 10. Must be able to measure Thermophoresis in 16 capillaries in less than 15minutes 11. Sample volume of less than 5ul 12. Must include software for control of the device and MST data evaluation 13. Must be able to be installed on a bench top 14. Must include a capillary tray. Disclaimer and Important Notes This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s). All capability Statements sent in response to this SOURCES SOUGHT notice must be submitted electronically (via email) to Rashida Ferebee, Contracting Officer, at ferebeers@nhlbi.nih.gov in either MS Word or Adobe Portable Document Format (PDF), by June 27, 2012, 9:00 AM, EST. All responses must be received by the specified due date and time in order to be considered.
 
Web Link
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NHLBI/NHLBI-CSB-(TR)-2012-175-RSF/listing.html)
 
Place of Performance
Address: NIH/NCATS, Rockville, Maryland, 20850, United States
Zip Code: 20850
 
Record
SN02779042-W 20120620/120618235408-19531fd75d7018bd9d002e537965bf5a (fbodaily.com)
 
Source
FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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