SOURCES SOUGHT
66 -- Dual Excitation and Emission Microscope and Equipment
- Notice Date
- 1/7/2016
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, Maryland, 20892, United States
- ZIP Code
- 20892
- Solicitation Number
- HHS-NIH-NIDA-SSSA-SS-16-103
- Archive Date
- 2/1/2016
- Point of Contact
- Jennifer Burns, Phone: 3014024592
- E-Mail Address
-
jennifer.burns2@nih.gov
(jennifer.burns2@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Description: This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Background: The National Institutes of Health (NIH) is the nation’s leading medical research agency and the primary Federal agency whose mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability, conducting, supporting and making medical discoveries that improve people’s health and save lives. The National Institute of Mental Health (NI MH ), MH IR Unit on Neural Computation and Behavior is a part of the National Institutes of Health (NIH), conducting research. Purpose and Objectives: The MH IR Unit on Neural Computation and Behavior for the National Institute of Mental Health has a potential requirement for a dual excitation and emission microscope, a pipette puller, and a micromanipulator. This microscope is needed to perform neural and behavioral research. Project requirements: The following brand-name or equal item may be required: 1. A moving objective Dual Excitation and Emission Microscope, and related accessories that contain the specifications listed below. · Ability to move objective 25mm in three axes with sub-micron accuracy · Ability to tilt microscope for imaging surfaces other than horizontal. · Pentagonal detector head allows 2 or 4 channel imaging without the need for dichroic beam splitters, thus increasing signal strength by limiting the number of optical elements in the emission path. · Short path detector head places collection path within 60mm of objective back aperture · Wide path detector head employs 50mm collection optics · Entire scope built on large rail so scope can be moved out of the way for easy placement of preparation under objective. · Scope has a very limited foot print so it is easy to place other equipment, manipulators for example, around the scope. · Moving/rotating element covered under European Patent: EP1438625 · Limited optical elements in excitation path produces minimal pulse dispersion. · Does not require pre-chirped laser source · Resonant scan box entirely enclosed to limit audible noise from resonant scanners · Works with Sutter commercial scanning software, MScan2.0 as well as ScanImage and other freewares. · Custom horizontal mount gives objective tilt to 90 degrees from vertical in both clockwise and counter clockwise directions. · Custom horizontal mount gives more access underneath objective for behaving animals and virtual reality displays. 2. Micro-Pipette puller that contains the specifications listed below. · Pulls electrodes with tip diameters less than 1.0μm consistently and reliably. · Measures velocity of the system as the glass softens and begins to pull apart under a constant load. The adjustable velocity allows for selection of a precise glass temperature as the trip point for the hard pull. Patent # 4,600,424. · Capable of storing 100 different programs to facilitate use by more than one · investigator. Each program consists of a maximum of 8 cycles. · Capable of storing 100 different programs to facilitate use by more than one · investigator. Each program consists of a maximum of 8 cycles. · “Ramp Test” allows for rapid adjustment of program parameters when a new filament or glass is introduced. · Constant current power supplies for filament and pull solenoid. · Looping pull cycle for fabrication of patch clamp pipettes. · Rapid cooling of the electrode heater creates fine tipped pipettes with extremely short tapers, thereby producing stiff pipettes suitable for beveling. · Humidity control chamber encloses glass during pull sequence for improved reproducibility. Patent Pending. · A completely self-contained air supply with humidity control and built in filtration system. · A complete “brown out” sensing circuit has been incorporated to shut down the unit when lie voltage drops below a critical level. When line voltage returns, the instrument automatically powers up and restores itself without the loss of program values. 3. Motorized Micromanipulator · Highly stable for experiments intolerant of pipette drift · Submicron (62.5) minimal resolution for fine movement · 25mm of motorized travel on all three axes · 4 th axis for coaxial movement of pipette, angle selected by DIP switches on ROE · Rotary Optic Encoder (ROE) button press actuates move to home position for pipette exchange · Rotary Optic Encoder (ROE) button press actuates move to work position near recording location · Continuous display (in microns) of axes positions located on ROE · DIP switches on rotary optic encoder (ROE) select direction of movement produced by turn of ROE knob · Modularized, compact design easily adaptable to set-up · Universal mounting system for headstage or pipette holder · Mounting adapters included with manipulator Anticipated period of performance: The microscope and equipment shall be delivered within 30 days after receipt of order. Capability statement /information sought. The respondent’s response shall also include any other specific and relevant information related to the requirements of this project that will enable the Government to determine the capabilities of the company to provide the specialized equipment described in this synopsis. Interested organizations must demonstrate and document in any response submitted, to this market survey extensive experience with and the ability to perform all of the specialized requirements elsewhere described. The respondent must also provide their DUNS number, organization name, address, point of contact, and size and type of business (e.g., 8(a), HubZone, etc.) pursuant to the applicable NAICS code and any other information that may be helpful in developing or finalizing the acquisition requirements. The information submitted must be must be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein. A cover page and an executive summary may be included but is not required. The response is limited to ten (10) page limit. The 10-page limit does not include the cover page, executive summary, or references, if requested. The response must include the respondents’ technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses. All responses to this notice must be submitted electronically (facsimile responses are NOT accepted ) to: Jennifer Burns Contract Specialist NIH\NIDA\SSSA jennifer.burns2@nida.nih.gov The response must be received on or before January 17, 11:00 AM (EST). Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization’s qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-2/HHS-NIH-NIDA-SSSA-SS-16-103/listing.html)
- Place of Performance
- Address: 35 Convent Drive, Building 35, Room 1002, Bethesda, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN03985780-W 20160109/160107234832-2f6f11a101796aca775f972f44df6fa5 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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