SOURCES SOUGHT
Q -- KNOCK-IN MOUSE MODEL
- Notice Date
- 4/28/2016
- Notice Type
- Sources Sought
- NAICS
- 541711
— Research and Development in Biotechnology
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, Nat'l Institute of Diabetes, Digestive, & Kidney Diseases, 2 Democracy Plaza, Suite 700W, 6707 Democracy Blvd., MSC 5455, Bethesda, Maryland, 20892-5455
- ZIP Code
- 20892-5455
- Solicitation Number
- NIHNICHD16051
- Archive Date
- 5/24/2016
- Point of Contact
- Verne Griffin,
- E-Mail Address
-
verne.griffin@nih.gov
(verne.griffin@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- This Small Business Sources Sought Notice is for information and planning purposes only and shall not be construed as a solicitation or as an obligation or commitment by the Government. This notice is intended strictly for Market Research. The National Institutes of Health (NIH), Eunice Kennedy Shriver National Institute of Child Health and Human Development is conducting a market survey to determine the availability and technical capability of qualified small business, veteran-owned small business, service-disabled veteran-owned small business or HUBZone small businesses capable of providing Knockin of IRES cre into the Rgs7 Gene in a Mouse. The National Institute of Diabetes, Digestive Diseases, and Kidney Diseases (NIDDK) has a requirement to generate a Rgs7 promoter-driven Cre recombinase-expressing knock-in custom mouse model. This custom mouse model will enable the conditional modification and expression of genes within Rgs7-expressing neurons of the central and peripheral nervous system and in neuroendocrine cells, and allow in depth study of G protein signaling pathways and regulation in those cells. This includes in particular G protein signaling regulated by the R7bp/G beta5/R7-RGS protein complex. Custom mouse containing knock-in of IRES-cre into the Rgs7 Gene, and after ubiquitous Flp breeding to remove neo cassette, must be available within 40 weeks after contract completed and accepted by both parties, and project initiated. The intended procurement will be classified under North American Industrial Classification (NAICS) code 541711 with a size standard of 500. Offerors who are capable of providing at a minimum, fifty-one percent (51%) of the required/actual services of this solicitation. All respondents are requested to identify their firm's size and type of business. Interested firms responding to this market survey must provide (a) capability statement demonstrating their experience, skills and capability to fulfill the Government's requirements for the above. The capability statement shall be in sufficient enough detail, but not to exceed 15 pages, so that the Government can determine the experience and capability of your firm to provide the requirements above. Your capability statement, not to exceed 15 pages, should include references. Capability statement must be received at verne.griffin@nih.gov no later than 10 days prior to close of business (11:00 A.M. local time at designated location) on May 9, 2016. For questions regarding Solicitation number NIHCHD16051 please send via email to verne.griffin@nih.gov. Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provided feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate response to a solicitation. Confidentiality - No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s)." PLEASE NOTE: In order to receive an award, contractor must be registered and have valid certification in the System For Award Management (SAM) http://www.sam.gov
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDDKD/NIHNICHD16051/listing.html)
- Record
- SN04098700-W 20160430/160428234832-8b067ebd9fc7f1d31ea7cedda936b807 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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