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FBO DAILY - FEDBIZOPPS ISSUE OF JUNE 03, 2017 FBO #5671
DOCUMENT

66 -- Intent to Sole Source - Molecular Devices’ SpectraMax M5 Multimode Reader - Attachment

Notice Date

6/1/2017
 

Notice Type

Attachment
 

NAICS

334516 — Analytical Laboratory Instrument Manufacturing
 

Contracting Office

US Department of Veterans Affairs;Veterans Health Administration;Service Area Office (SAO) East;323 North Shore Drive, Suite 500;Pittsburgh PA 15212-5319
 

ZIP Code

15212-5319
 

Solicitation Number

VA24017Q0150
 

Archive Date

9/8/2017
 

Point of Contact

Lynn Portman
 

Small Business Set-Aside

N/A
 

Description

The Department of Veterans Affairs, Northport VA Medical Center intends to pursue a sole source procurement in accordance with FAR 6.302-1 for the Molecular Devices SpectraMax M5 Multimode Reader. The Molecular Devices SpectraMax M5 Multimode Reader has patented features that will minimize errors, limitations, while expanding the dynamic range of the assays we will be performing to characterize the fungal sphingolipid biosynthesis pathway. This device will be utilized to measure ABS, FI, Lum, TRF, and FP for various assays examining the role of various enzymes in the fungal sphingolipid biosynthesis pathway. Mutant strains targeting specific genes as well as isolated enzymes will be tested in various assays using microplates as well as cuvettes. The assays will be used to create growth curves (ABS), characterize mutant strains (ABS, FI, Lum), measure enzymatic products (ABS, FI, Lum), and characterize enzymatic behaviors (TRF, FPI).These features, listed below, are only available on Molecular Devices SpectraMax M5 Multimode Reader: Molecular Devices SpectraMax M5 Multimode Reader offers the following patented features that optimize the equipment for the assays we will be performing: · AutoPMT capability- Automatic Photomultiplier Tube (PMT) setting (U.S. Patent No. 6,232,608) that adjusts the optimum voltage for each well s sample concentration and then normalizes the raw data to show Relative Fluorescence Units (RFU) values. Wells are then selectively re-read at the optimal PMT setting. Photo-bleaching is eliminated because wells are not read unnecessarily. · Unique optical system- Reader utilizes U.S. Patent No. 6,097,025 for a light detection device having an optical path switching mechanism. Molecular Devices is the sole source for microplate readers that switch between top- and bottomread optical paths as described in US Pat. No. 6,097,025. Reader also utilizes U.S. Patent No. 6,316,774 for its unique optical system design for a scanning fluorometer. Molecular Devices is the sole source for microplate readers incorporating the optical design as described in US Pat. No. 6,316,774. · Path Check Pathlength Sensor- PathCheck Sensor (U.S. Patents 5,959,738, 6,188,476, 6,320,662, 6,339,472, 6,404,501, 6,496,260 and 6,995,844). This is the only sensor of its kind not affected by temperature, and requires no accessories to measure the pathlength of the sample in all individual microplate wells. The pathlength measurement can be used to calculate concentrations without a standard curve, test liquid handling devices, detect and correct for pipetting errors, and expand the dynamic range of the assay. · Dual Monochromator Fluorescence detection- Reader utilizes U.S. Patent Nos. 6,236,456 and 6,313,471 for dual monochromator optical system for a scanning fluorometer. Molecular Devices is the sole source for microplate readers incorporating the dual-monochromator architecture as described in US Pat. Nos. 6,236,456 and 6,313,471. · Microplate heating system- Reader utilizes U.S. Patent No. 6,693,709 for the design of the plate heating mechanism. Molecular Devices is the sole source for microplate readers incorporating the plate heating technology as described in US Pat. No. 6,693,709. Multimode light detection- Reader utilizes U.S. Patent No. 6,825,921 for its unique multimode light detection system. Molecular Devices is the sole source for microplate readers incorporating the multimode detection system as described in US Pat. No. 6,825,921. This notice of intent is not a request for competitive proposals; however, any responsible source who believes it is capable of meeting the requirement may submit a capability statement to the contracting office no later than June 8th, 12:00, EST. Interest/capability statements may be sent to Lynn Portman at lynn.portman@va.gov. No telephone responses will be accepted. A determination not to compete the proposed requirement based upon the responses to this notice is solely within the discretion of the Government.
 

Web Link

FBO.gov Permalink
(https://www.fbo.gov/notices/343e0656bc990a24c977c46d62128e48)
 

Document(s)

Attachment
 

File Name: VA240-17-Q-0150 VA240-17-Q-0150.docx (https://www.vendorportal.ecms.va.gov/FBODocumentServer/DocumentServer.aspx?DocumentId=3542078&FileName=VA240-17-Q-0150-000.docx)

Link: https://www.vendorportal.ecms.va.gov/FBODocumentServer/DocumentServer.aspx?DocumentId=3542078&FileName=VA240-17-Q-0150-000.docx

 

Note: If links are broken, refer to Point of Contact above or contact the FBO Help Desk at 877-472-3779.
 

Record

SN04530024-W 20170603/170602000338-343e0656bc990a24c977c46d62128e48 (fbodaily.com)
 

Source

FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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