SPECIAL NOTICE
A -- Notice of Intent to Modify the contract “Generation R Study” with the Netherlands Organisation for Applied Scientific Research
- Notice Date
- 12/7/2017
- Notice Type
- Special Notice
- NAICS
- 541715
— Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Environmental Health Sciences, Office of Acquisitions, Office of Management, 530 Davis Drive, Durham, North Carolina, 27713, United States
- ZIP Code
- 27713
- Solicitation Number
- NIHES2018-GENR
- Archive Date
- 12/25/2017
- Point of Contact
- Jennifer Smith, Phone: 984-287-3059
- E-Mail Address
-
smithj3@niehs.nih.gov
(smithj3@niehs.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Pursuant to Federal Acquisition Regulations (FAR) 5.201(b) (1) (ii), the National Institute of Environmental Health Sciences (NIEHS) intends to negotiate a contract modification under authority of FAR 52.243-2 with the Netherlands Organisation for Applied Scientific Research (hereinafter "TNO") under contract HHSN273201500003C entitled "Support of Collaborative Studies of Exposure to Environmental Contaminants in Relation to Child Health in the Generation R Study." The "Generation R Study" began in Rotterdam, Netherlands more than 14 years ago as a large effort to enroll and follow pregnant women and their children over an extended period of time. Nearly all pregnant women in Rotterdam were eligible and enrollment began in 2002. Almost 10,000 pregnant women and their offspring were enrolled. Women in the study provided biologic specimens and completed questionnaires about themselves and their children, and in-person follow-up examinations are continuing to take place on a regular basis. The Generation R Study has many specific goals, although the general purpose of the study is to find the causes of serious diseases among mothers and children. The particular interests of NIEHS in the Generation R Study is in metabolomic and environmental exposures as reflected by measurements in urine specimens. In order to strengthen the Generation R Study in this area, NIEHS has, in past years, contracted for the collection of extra maternal urine samples during pregnancy to be stored in the Netherlands for assessment of environmental exposures. Specifically, 22.5 ml of urine was designated for use in NIEHS-sponsored analyses. Under the current contract with TNO, NIEHS investigators select urine specimens for analysis, get the specimens analyzed, and then relate the results to child development to identify adverse effects. All access to or use of these biomaterials, data, and specimens by NIEHS must be through collaboration with Netherlands researchers at TNO since they are the only ones with access to the proprietary biospecimens and data. The current R&D contract with TNO referenced in this notice was awarded on June 17, 2013 and expires on June 16, 2018. Important scientific findings under the contract and evolving discoveries in the epidemiological arena have resulted in the need to extend the current contract to continue support of the Generation R study and continue scientific projects based on findings. NIEHS intends to modify the contract to extend the period of performance for an additional five years to allow adequate time to accomplish the necessary support and studies. This change will be accomplished under authority of FAR 52.243-2 and is determined to be within the scope of the current contract specifications. There is no material difference between the modified contract and the contract that was originally awarded, as the R&D specifications were drafted broadly to accommodate uncertainties and variation inherent in this type of research. This Notice of Intent is to provide information regarding the government's intent to modify the contract. This notice is NOT a request for competitive proposals and a solicitation will not be issued. Parties may express their interest to the Contracting Officer no later than 4 pm, Eastern Standard Time on December 20, 2017. Interested parties should submit no more than 5 pages explaining how they can meet this government's requirement.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIEHS/NIHES2018-GENR/listing.html)
- Place of Performance
- Address: The Netherlands, Netherlands
- Record
- SN04760881-W 20171209/171207231702-31f48efa93a1a2b0fd682ba2e5aacbae (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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