SOURCES SOUGHT
B -- Analysis of Unique Neurodevelopmental Disorder Data
- Notice Date
- 2/22/2018
- Notice Type
- Sources Sought
- NAICS
- 541720
— Research and Development in the Social Sciences and Humanities
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, 6001 Executive Boulevard, Room 4211, MSC 9559, Bethesda, Maryland, 20892-9559, United States
- ZIP Code
- 20892-9559
- Solicitation Number
- NIHDA201800063-SS
- Archive Date
- 3/14/2018
- Point of Contact
- Danielle R. Brown, Phone: 3014802385
- E-Mail Address
-
danielle.brown2@nih.gov
(danielle.brown2@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Federal Business Opportunities (FBO) SOURCES SOUGHT NOTICE 1.Solicitation Number: NIHDA201800063-SS 2.Title: Analysis of Unique Neurodevelopmental Disorder Data 3.NAICS Code: 541720 - Research and Development in the Social Sciences and Humanities 4.Size Standard: $20.5 Million 5.Description: This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Background: The Genetic Basis of Mood and Anxiety Disorders Section, within the Human Genetics Branch, NIMH-IRP, is a clinical genetics research program with both human-subjects and laboratory components. Our leadership position depends critically on recruitment of family study volunteers, competent performance of structured diagnostic assessments in the field, refinement of diagnostic procedures, and the collection of research specimens. Ongoing research is focused on volunteers of Amish or Mennonite ancestry, who must usually be ascertained, enrolled, and assessed in the field. Purpose and Objectives: The purpose of this order is to procure contractor support services to analyze clinical data from participants from collaborative protocols within the Neurodevelopmental and Behavioral Phenotyping Service (NBPS), including a project characterization of youth with sex chromosome aneuploidies the vendor will use laboratory resources (NIH issued laptop) to analyze clinical data from subjects. The vendor will write and edit manuscripts for submission and will serve as a co-author on additional papers. The Neurodevelopmental and Behavioral Phenotyping Service, National Institute of Mental Health, conducts clinical research on a variety of childhood behavioral problems including research to identify clinical factors which influence the onset and expression of behavioral symptoms. Identifying behavioral phenotypes will aid in the development of more effective treatment and prevention strategies for childhood disorders. Project requirements: This contract will allow the vendor to analyze data from several ongoing projects in which the vendor had collected the data through behavioral assessments. These projects include analysis of data from children and adults with sex chromosome aneuploidies (SCA) and several other genetic disorders that are characterized through neurodevelopmental assessments in the Neurodevelopmental and Behavioral Phenotyping Service (NBPS). The vendor will use laboratory resources (NIH issued laptop) to analyze data and will then characterize and determine the presence of neurodevelopmental disorders in this sample. The vendor will write, contribute to, and edit manuscripts for submission and will serve as co-author on additional papers. Please see the attached Statement of Work (SOW) for further details. Period of Performance: One year from date of award. Capability statement /information sought. Please provide a capability statement, this includes: •Provide evidence the respondent has performed services. •Provide evidence of similar previous contracts of research of the same magnitude. •Information regarding (a) staff expertise, including their availability, experience, and formal and other training; (b) current in-house capability and capacity to perform the work; (c) prior completed project of similar nature; (d) corporate experience and management capability; and (e) examples of prior completed Government contracts, references, and other related information. Please provide your DUNS number, organization name, address point of contact, and size and type of business (e.g., 8(a), HubZone, etc.,) pursuant to the applicable NAICS code and any other information that may be helpful. One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2" x 11" paper size, with 1" top, bottom, left and right margins, and with single or double spacing. The information submitted must be must be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein. The response is limited to one to two (1-2) page limit. The 1-2 page(s) does include the cover page, executive summary, or references, if requested. All responses to this notice must be submitted electronically to the Contract Specialist and Contracting Officer. Facsimile responses are NOT accepted. The response must be submitted to Danielle R. Brown, Contract Specialist, at Danielle.brown2@nih.gov. The response must be received on or before Tuesday, February 27, 2018 at 11:00AM, Eastern Standard Time. No extensions to the deadline will be granted. "Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s)." STATEMENT OF WORK (SOW) - SERVICES GENERAL INFORMATION Title of Project: Analysis of Unique Neurodevelopmental Disorder Data Statement of Need, Purpose, and/or Objective: The purpose of this order is to procure contractor support services to analyze clinical data from participants from collaborative protocols within the Neurodevelopmental and Behavioral Phenotyping Service (NBPS), including a project characterization of youth with sex chromosome aneuploidies the vendor will use laboratory resources (NIH issued laptop) to analyze clinical data from subjects. The vendor will write and edit manuscripts for submission and will serve as a co-author on additional papers. Background Information: The Neurodevelopmental and Behavioral Phenotyping Service, National Institute of Mental Health, conducts clinical research on a variety of childhood behavioral problems including research to identify clinical factors which influence the onset and expression of behavioral symptoms. Identifying behavioral phenotypes will aid in the development of more effective treatment and prevention strategies for childhood disorders. Period of Performance: One year from date of award. Background Information: The Neurodevelopmental and Behavioral Phenotyping Service, National Institute of Mental Health, conducts clinical research on a variety of childhood behavioral problems including research to identify clinical factors which influence the onset and expression of behavioral symptoms. Identifying behavioral phenotypes will aid in the development of more effective treatment and prevention strategies for childhood disorders.. SCOPE OF WORK General Requirements: Independently and not as an agent of the Government, the Contractor shall furnish all the necessary services, qualified personnel, material, equipment, and facilities, not otherwise provided by the Government as needed to perform the Statement of Work below: Specific Requirements: This contract will allow the vendor to analyze data from several ongoing projects in which the vendor had collected the data through behavioral assessments. These projects include analysis of data from children and adults with sex chromosome aneuploidies (SCA) and several other genetic disorders that are characterized through neurodevelopmental assessments in the Neurodevelopmental and Behavioral Phenotyping Service (NBPS). The vendor will use laboratory resources (NIH issued laptop) to analyze data and will then characterize and determine the presence of neurodevelopmental disorders in this sample. The vendor will write, contribute to, and edit manuscripts for submission and will serve as co-author on additional papers. LEVEL OF EFFORT: GOVERNMENT RESPONSIBILITIES The vendor will use government owned computer in a telework capacity. The vendor will not need access to the National Institutes of Health, Building 10, Room 1C250. It is not anticipated that the vendor will require access to NIH facilities on federal holidays. DELIVERY OR DELIVERABLES The vendor will provide analysis of clinical data from children and adults with genetic disorders and neurodevelopmental problems such as intellectual disability and autism spectrum disorder. They will provide analysis of cognitive and behavioral data from these participants. The vendor will write and edit manuscripts for submission and will serve as a co-author on additional research papers. REPORTING REQUIREMENTS The vendor will provide results of the analysis of samples described above on a weekly basis. Manuscripts and research papers will be written when data compilation has been completed. OTHER CONSIDERATIONS Travel: Travel: Performance of the duties included in this contract will not involve any travel. All work will be completed at either the vendors approved telework location or the National Institutes of Health in Bethesda, MD. Key Personnel: The expectation for the key personnel is that they be an expert in neurodevelopmental disorders, and particularly have hand-on experience both conducting assessments. Key personnel should also be able to analyze data on pediatric populations including rare genetic disorders, autism spectrum disorder and severe and profound intellectual disability. Information System Security Plan: Contractor personnel performing work under this contract shall satisfy all requirements for appropriate security eligibility as specified in the sole-single source justification in dealing with access to sensitive information and information systems belonging to or being used on behalf of the Office of the Clinical Director. To satisfy those requirements, a Low Risk Background Investigation shall be conducted prior to performing work under this contract. Appropriate background investigation forms will be provided upon contract award, and are to be completed and returned to ORS/DPSAC within 30 days for processing. Contractors will be notified when the investigation has been completed and adjudicated. All costs associated with obtaining clearances for contractor-provided personnel will be the responsibility of the contractor. Further, the contractor will be responsible for the actions of all individuals provided to work under this contract. If damages arise from work performed by contractor-provided personnel under the auspices of this contract, the contractor will be responsible for all resources necessary to remedy the incident. Data Rights: The Office of the Clinical Director, NIMH shall have unlimited rights to and ownership of all deliverables provided under this contract, including reports, recommendations, briefings, work plans and all other deliverables. This includes the deliverables provided under the basic contract/order and any optional task deliverables exercised by the contracting officer. In addition, it includes any additional deliverables required by contract change. The definition of "unlimited rights" is contained in Federal Acquisition Regulation (FAR) 27.401, "Definitions." FAR clause 52.227-14, "Rights in Data-General," is hereby incorporated by reference and made a part of this contract/order. Section 508-Electronic and Information Technology Standards: The contractor shall comply with Section 508 of the Rehabilitation Act (29 U.S.C. § 794d), as amended by the Workforce Investment Act of 1998 (P.L. 105-220), August 7, 1998. Publications and Publicity: The vendor will be involved in data analysis, data entry, and writing and editing manuscripts for submission and will serve as a co-author on additional research papers. Confidentiality of Information: NIMH is providing information/data of a personal nature about individual(s) or proprietary information data, in the form of de-identified data from a study protocol, so although information is confidential, it will not be identifiable. The contract will include having such data be handled in accordance with the guidelines of the NIH IRB under which these protocols are approved, and which the contractor is listed as an investigator. Data will be stored on a password-protected server (behind the NIH firewall). ATTACHMENTS 1. Evaluation / Selection Criteria ATTACHMENT 1: Technical Evaluation Criteria Analysis of Unique Neurodevelopmental Disorder Data The Government will award a contract resulting from this requirement on the basis of best value, technical factors and price considered. Technical factors together shall be considered more important than price and all technical evaluation factors are detailed below: The proposal should be no longer than 3 pages, excluding key personnel resume(s)/curriculum vitae. Factor 1: Technical Approach (30 Points) The Contractor shall be evaluated for understanding of the requirements in accomplishing the statement of work. The offeror's technical approach shall indicate compliance with the requirements as outlined in the statement of work. Factor 2: Key Personnel (30 Points) The Contractor shall provide key personnel that are able to provide the following document experience, educational background and training, and availability of the proposed staff and their designated responsibility on the project. This includes the education, experience, managerial competence and time commitment of the proposed project manager and the experience, technical competence, and time commitment of other staff; staff expertise in travel logistics. Factor 3: Past Performance (40 Points) The Contractor shall provide at least two (2) past performance references with knowledge of the contractor's relevant skills and experience related to the requirements outlined in this Statement of Work. References shall include the following information: a)Name of Organization b)Description of Contractor's Responsibilities as they relate to this SOW c)Contract Period of Performance d)Contact Name and Title e)Telephone Number f)E-mail Address g)Contact Name, Title, and Telephone Number Past Performance shall be evaluated for relevance to the current requirement. Documented successful past performance reflecting knowledge of NIH policies and programs, meeting planning experience, and expertise in travel support. Technical proposals will be evaluated using a summary adjectival rating in accordance with the following scale: Excellent (90 - 100) Very Good (80 - 89) Good (70 - 79) Fair (60 - 69) Poor (0 - 59) Excellent The proposal has exceptional merit and reflects an excellent approach which will clearly result in the superior attainment of all requirements and objectives. This clearly achievable approach includes several advantageous characteristics of substance, and very few disadvantages, which can be expected to result in outstanding performance. The risk of unsuccessful performance is very low as the proposal provides solutions which are unquestionably feasible and practical. These solutions are further considered very low risk in that they are exceptionally clear and precise, fully supported, and demonstrate a clear understanding of the requirements. Risk Level: Very Low Very Good The proposal demonstrates a sound approach which is expected to meet all requirements and objectives. This sound approach includes advantageous characteristics of substance, and few relatively minor disadvantages, which collectively can be expected to result in satisfactory performance. The risk of unsuccessful performance is low as the proposal contains solutions which are considered feasible and practical. These solutions are further considered to reflect low risk in that they are clear and precise, supported, and demonstrate an understanding of the requirements. Risk Level: Low Good The proposal demonstrates an approach which is capable of meeting all requirements and objectives. The approach includes both advantageous and disadvantageous characteristics of substance, where the advantages are not outweighed by the disadvantages. Collectively, the advantages and disadvantages are likely to result in acceptable performance. The risk of unsuccessful performance is moderate, as the proposal solutions are generally feasible and practical. These solutions may also be considered to reflect moderate risk in that they may be somewhat clear and precise, partially supported, and/or demonstrate a general understanding of the requirements. Risk Level: Neutral. Fair The proposal demonstrates an approach which may not be capable of meeting all requirements and objectives. The approach has disadvantages of substance and advantages, which if they exist, are outweighed by the disadvantages. Collectively, the advantages and disadvantages present a low or questionable likelihood of resulting in satisfactory performance. The risk of unsuccessful performance is high as the proposal contains solutions which may not be feasible and practical. These solutions may also be considered to reflect high risk in that they lack clarity and precision, are generally unsupported, and/or do not demonstrate a complete understanding of the requirements. Risk Level: High Poor The proposal demonstrates an approach which, based on a very high risk, will very likely not be capable of meeting all requirements and objectives. This approach has several disadvantages of substance, and advantages which, if they exist, are outweighed by disadvantages. Collectively, the advantages and disadvantages are unlikely to result in satisfactory performance. The risk of unsuccessful performance is very high as the proposal contains solutions which are not feasible and practical. The solutions may also be considered to reflect very high risk in that they lack any clarity or precision. Risk Level: Very High
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