SPECIAL NOTICE
66 -- Sole Source Notice of Intent: Andor Dragonfly 505 Confocal System with PC computer, optical table, and associated software
- Notice Date
- 9/5/2018
- Notice Type
- Special Notice
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Environmental Health Sciences, Office of Acquisitions, Office of Management, 530 Davis Drive, Durham, North Carolina, 27713, United States
- ZIP Code
- 27713
- Solicitation Number
- NIHES201800023
- Point of Contact
- Onyenauche Washington,
- E-Mail Address
-
uche.washington@nih.gov
(uche.washington@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- THIS IS A NOTICE OF INTENT TO SOLE SOURCE AND NOT A REQUEST FOR QUOTATION; A solicitation document WILL NOT be issued and quotations will not be requested. The National Institute of Environmental Health Sciences (NIEHS), located in Research Triangle Park, North Carolina, intends to negotiate on a sole source basis with Andor Technology Ltd. (425 Sullivan Avenue, Suite #3, South Windsor CT 06074/DUNS: 049404507/CAGE Code: 1K9L7) to purchase an Andor Dragonfly 505 Confocal System (with PC computer, optical table, and associated software) to support the Fluorescence Microscopy and Imaging Center (FMIC) of the Signal Transduction Laboratory (STL). This acquisition is conducted under the authority of the Federal Acquisition Regulations (FAR) Subpart 13.106-1 (b) Soliciting from a single source, only one responsible source and no other supplies or services will satisfy agency requirements in conjunction with FAR Part 12, Acquisition of Commercial Items. The FAR as supplemented by the Health and Human Services Acquisition Regulation (HHSAR) will be used to evaluate the quote and award this requirement. The North American Industry Classification System (NAICS) code for this requirement is 334516 "Analytical Laboratory Instrument Manufacturing" and has a size standard of 1,000 employees. The mission of the NIEHS is to discover how the environment affects people in order to promote healthier lives. The Branches & Laboratories at NIEHS fall under the Intramural Research and the National Toxicology Program (NTP) Divisions. The overall goal of the STL is to define the mechanisms that cells, tissues and organisms use to respond to physiological and environmental stimuli. The FMIC is a common use facility, under the STL. The FMIC provides NIEHS researchers and their collaborators, access to a variety of advanced imaging equipment and techniques. In addition, the center's experienced staff offers hands on training on the image acquisition and the data analysis. The goal of the center is to ensure that our users are able to easily utilize some of the most cutting edge technology available to further their research. The FMIC provides researchers access to a variety of techniques that push the envelope on 3D cellular imaging. Most of the techniques are centered on obtaining digitized images of fluorescent cells from a confocal microscope. The FMIC currently has 4 point scanning confocal microscopes and now needs to broaden its imaging capability with a multi-modal imaging system that contains 1) multi-point confocal for fast scanning, 2) simultaneous dual color TIRF, and 3) Super-Resolution down to 20nm resolution. As such, the FMIC is in need of an Andor Dragonfly 505 Imaging System to help increase the live cell imaging capability and to complement the existing Super-Resolution technology within the FMIC. The Andor Dragonfly 505 Confocal System (with PC computer, optical table, and associated software) offers a unique set of testing capabilities and features that are not available on any other commercially available system. The an Andor Dragonfly 505 Confocal System (with PC computer, optical table, and associated software) offers the following capabilities and features: • Must allow for imaging of biological samples with super-resolution, live cell capability, and through deep tissue that has been optically cleared. • Must provide state of the art imaging resources to intramural researchers. • Must provide instrumentation access and data analysis capability for a large number of investigators. • Must provide multi-point confocal technology with the ability to greatly decrease scanning time. The standard multi-point confocal technology is the "spinning disk" but traditional methods of spinning disk confocal microscopes do not perform well when imaging thick tissue due to • Must provide pinhole-pinhole crosstalk and non-uniform illumination. • Must have a spinning disk confocal that greatly reduces pinhole-pinhole crosstalk while also having a flat field of illumination. • Must enable successful scans of thick, cleared tissue at speeds 5X faster than the point-scanning technology currently employed in the FMIC. • Must possess amulti-point confocal for high temporal imaging at 400 frames per second with an option of 2 pinhole choices, Borealis illumination to prevent pinhole-pinhole crosstalk with a uniform field of view, a second camera port with 4 positions available for port and chromatic switching for dual color simultaneous capture, simultaneous dual color Total Internal Reflection Fluorescence (TIRF), 3D localization microscopy optics for dSTORM, and GPU accelerated Deconvolution with parallel processing during image capture. • Must provide high uniformity illumination and NIR imaging, zoom illumination optics of 4x, 16x & 36x power density, and camera zoom optics of 1.0x, 1.5x and 2.0x for optimum resolution across different objective magnifications and camera pixel sizes. • Software must include real-time 3D visualisation, GPU accelerated deconvolution, and file saving in Imaris format for downstream data editing, surface rendering, annotation, snapshots and sophisticated movie production. • Must provide seamless integration with the Bitplane lmaris software that is currently used by the FMIC. • Must have the ability to quickly load image data into standard FMIC workflow • Must have speed learning of the new system and hasten productive image analysis. The Contractor shall provide shipping/delivery, installation, introductory training, and a one year warranty. This notice of intent is NOT a request for competitive proposals; however, all responses received within five (5) days from the date of publication of this synopsis will be considered by the Government. A determination by the Government not to compete this proposed contract action based upon responses to this notice is solely with the discretion of the Government. Information received will normally be considered for the purpose of determining whether to conduct a competitive procurement. If no affirmative responses are received within five (5) days of this notice to determine whether a qualified source is more advantageous to the Government, the order will be issued to Andor Technology Ltd. There is no solicitation package available. The Contracting Officer for this requirement is Ms. Onyenauché Washington. All questions or concerns relating to this notice shall be submitted by e-mail to uche.washington@nih.gov
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIEHS/NIHES201800023/listing.html)
- Place of Performance
- Address: NIH/NIEHS/DIR/STL/Fluorescence Microscopy and Imaging Center, 111 TW Alexander Drive, Research Triangle Park, North Carolina, 27709, United States
- Zip Code: 27709
- Zip Code: 27709
- Record
- SN05072551-W 20180907/180905230907-a0c7407a2bae476ba04e9c66d2caa701 (fbodaily.com)
- Source
-
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