SOURCES SOUGHT
66 -- Small Animals In Vivo imaging (IVIS) and Anesthesia Systems
- Notice Date
- 5/21/2020 10:53:06 AM
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH NIDA Bethesda MD 20892 USA
- ZIP Code
- 20892
- Solicitation Number
- HHS-NIH-NIDA-SB-SS-20-006748
- Response Due
- 5/29/2020 9:00:00 AM
- Archive Date
- 09/30/2020
- Point of Contact
- Debra C. Hawkins, Phone: 3018277751
- E-Mail Address
-
Debra.Hawkins@nih.gov
(Debra.Hawkins@nih.gov)
- Description
- Description: This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition.� It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract.� Responses will not be considered as proposals or quotes.� No award will be made because of this notice.� The Government will NOT be responsible for any costs incurred by the respondents to this notice.� This notice is strictly for research and information purposes only. Background / Purpose / Objective:� In order to gain a better understanding of the molecular and anatomical changes occurring in aging and disease progression there is a need to longitudinally� track cells and molecules in living animals. The IVIS platform supports� the non-invasive monitoring of both� bioluminescence and fluorescence probes in three-dimensions (3D) within small animal models (rats and mice).� The IVIS platform offers imaging solutions for a wide range of applications within the IRP biomedical research including oncology, infectious disease, musculoskeletal, cardiovascular, neurology, respiratory and stem cell research. Pharmacokinetics/ pharmacodynamics studies and analysis are also possible using the IVIS platform.� � The intent of this action is to purchase an IVIS Instrument and the small animal anesthesia system with associated hardware and software. The system should be brand-name or equal to the IVIS system manufactured by PerkinElmer Health Sciences Inc., 710 Bridgeport Avenue, Shelton, CT 06484-4794; Telephone number: 800-762-4000.� The system includes the following: (1) One (1) each, Product number: 124262, Description:� IVIS Instrument, Spectrum, 120V, Andor C.� The IVIS� Spectrum in vivo imaging system uses a novel patented optical imaging technology to facilitate non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals in both 2D and 3D; (2) Number: 49410; Description: Imaging System Installation; (3) Number: 122842; Description: 2 Day Advanced Imaging Field Training; (4) Delivery and Installation; (5) Number: CLS146737, Description: Rodent Anesthesia System, RAS-4.� The RAS-4 allows researchers to use real-time in vivo imaging to monitor molecular and genetic activity within mice or rats. The system allows delivery of isoflurane via 4 ports to run 2 instruments simultaneously offering the ultimate in flexibility; (6) Extended Warranty includes one (1) year warranty (parts, labor, and travel), and 1-preventative maintenance visit for the IVIS Spectrum 120V.� and (7) Number: CLS149578, Description: IWB-60 Workbench, 60"", 1000lb Capacity. Salient characteristics: For advanced fluorescence pre-clinical imaging, the IVIS Spectrum has the capability to use either trans-illumination (from the bottom) or epi-illumination (from the top) to illuminate in vivo fluorescent sources. 3D diffuse fluorescence tomography can be performed to determine source localization and concentration using the combination of structured light and trans illumination fluorescent images. The instrument is equipped with 10 narrow band excitation filters (30nm bandwidth) and 18 narrow band emission filters (20nm bandwidth) that assist in significantly reducing autofluorescence by the spectral scanning of filters and the use of spectral unmixing algorithms. In addition, the spectral unmixing tools allow the researcher to separate signals from multiple fluorescent reporters within the same animal.�� The RAS-4 Rodent Anesthesia System is compatible with our suite of in vivo preclinical imaging systems including IVIS� IVIS system: (1) High-sensitivity in vivo imaging of fluorescence and bioluminescence; (2) High throughput (5 mice) with 23 cm field of view; (3) High resolution (to 20 microns) with 3.9 cm field of view; (4) Twenty eight high efficiency filters spanning 430 � 850 nm; (5) Supports spectral unmixing applications; (6) Ideal for distinguishing multiple bioluminescent and fluorescent reporters; (7) Optical switch in the fluorescence illumination path allows reflection-mode or transmission-mode illumination; (8) 3D diffuse tomographic reconstruction for both fluorescence and bioluminescence; (9) Ability import and automatically co-register CT or MRI images yielding a functional and anatomical context for your scientific data; (10) NIST traceable absolute calibrations; (11) Gas anesthesia inlet and outlet ports; and (12) Class I Laser Products Anesthesia system; (1) Uses isoflurane gas # two fixed 500 cc/min (1.0 LPM) circuits and two adjustable (0-4 LPM) circuits; (2) Dedicated FMT quick connect outlet; (3) Provides gas to two instruments, induction chamber and benchtop accessory simultaneously; (4) Dedicated vacuum pump with adjustable flowmeters to monitor and direct flow to specific ports as required; (5) Key filled Isoflurane vaporizer for improved safety; (6) Isoflurane-absorbing disposable charcoal filters absorb excess gas, as well as limit gas escaping into the surrounding laboratory environment; (7) Large sight glass to monitor available isoflurane supply; and (8) Lightweight with carrying handle for portability and small footprint to save valuable bench space. Anticipated period of performance / delivery date:� The Government�s anticipated delivery period is thirty (30) days after receipt of order. ��� Other important considerations: The response may cite any other information that is necessary for potential respondents to understand the nature of the potential requirement or proposed acquisition. Capability statement /information sought.� The respondents must submit clear and convincing evidence that their product is equivalent or superior to the brand-name product specified in this notice.� The response shall include: the unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered to determine the method of acquisition.� The infoes, addresses, telephone and fax numbers, and e-mail addresses. The response must be clear and concise in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2� x 11� paper size, with 1� top, bottom, left and right margins, with single or double spacing, and limited to ten (10) pages (exclusive of the cover page, executive summary, or references, if requested). All responses to this notice must be submitted electronically to Debra C. Hawkins Contractor, Acquisition Policy Analyst II, at debra.hawkins@nih.gov on or before May 29, 12:00 PM.� Facsimile responses are NOT accepted. Disclaimer and Important Notes:� This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization�s qualifications to provide the product or perform the services specified herein. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).�
- Web Link
-
SAM.gov Permalink
(https://beta.sam.gov/opp/0fb7198361794a8f9374747190eee953/view)
- Place of Performance
- Address: Baltimore, MD 21224, USA
- Zip Code: 21224
- Country: USA
- Zip Code: 21224
- Record
- SN05668436-F 20200523/200521230232 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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