SPECIAL NOTICE
99 -- FLEXCELL TENSION SYSTEM BRAND NAME
- Notice Date
- 8/2/2022 11:39:52 AM
- Notice Type
- Special Notice
- NAICS
- 423490
— Other Professional Equipment and Supplies Merchant Wholesalers
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH Bethesda MD 20892 US
- ZIP Code
- 20892
- Solicitation Number
- NIHOLAO6384659
- Response Due
- 8/7/2022 12:00:00 PM
- Point of Contact
- van v holley, Phone: 2025949439
- E-Mail Address
-
holleyv@od.nih.gov
(holleyv@od.nih.gov)
- Small Business Set-Aside
- SBA Total Small Business Set-Aside (FAR 19.5)
- Description
- THIS IS A NOTICE OF INTENT TO AWARD A SOLE SOURCE CONTRACT AND IS NOT A REQUEST FOR COMPETITIVE QUOTES.� IAW FAR 6.302-1(a) - Only One Responsible�Source and No Other Supplies or Services Will Satisfy Agency Requirements -�this purchase order is intended to be awarded as a sole source procurement�to FLEXCELL INTERNATIONAL, FlexCell Inc. confirms that it is the only authorized U.S. Supplier of the Flexcell� FX6000� Tension System. FlexCell owns all applicable and pending patents as well as control the manufacture and distribution rights to the instrumentation. The recently described Piezo1, like ion channels, are among the most specific and sensitive mechanotransducers that translate extracellular mechanical forces to intracellular molecular signaling cascades. Our data show that the Piezo1 is expressed also in retinal microglia cells, which is important for maintaining retinal homeostasis and involved in many pathological processes in retinal diseases, such as age-related macular degeneration, glaucoma, and diabetic retinopathy. To further understand the Piezo1 function in microglia cell activation and motility, we produced a Piezo1 knockout microglia cell line which can be used to monitor and explore Piezo1 function in microglia cells. We need to compare gene expression, morphology, and physiologic changes in microglia cells with and without Piezo1 in both single dish and 6-well plates under the tension/strength system. The Flexcell� FX6000� Tension System from FlexCell is the only one that can do cell strength in both 6-well plates and dishes. �The manufacturer only sells directly and there are no resellers. This notice of intent is not a request for competitive proposals.� However,�all proposals received by the date specified herein will be�considered by the Government. A determination by the Government not to�compete with this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will�normally be considered solely for the purpose of determining whether to conduct a competitive procurement. Interested parties may identify their interest and may submit a quote and/or capability statement by 3:00 PM EST, 7 August 2022, which shall be considered by the Government.�Capability statements and quotes shall be sent via email to�holleyv@od.nih.gov. Attachments: J&A, Flexcell Tension System
- Web Link
-
SAM.gov Permalink
(https://sam.gov/opp/720f6ef2adbd48c0a09cc1e9a3c411db/view)
- Place of Performance
- Address: Bethesda, MD 20892, USA
- Zip Code: 20892
- Country: USA
- Zip Code: 20892
- Record
- SN06410394-F 20220804/220802230116 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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