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SAMDAILY.US - ISSUE OF SEPTEMBER 16, 2023 SAM #7963
SOLICITATION NOTICE

65 -- ANTI-ANTHRAX TOXIN ANTIBODY, RAXIBACUMAB

Notice Date
9/14/2023 11:25:02 AM
 
Notice Type
Combined Synopsis/Solicitation
 
NAICS
325413 — In-Vitro Diagnostic Substance Manufacturing
 
Contracting Office
FDA OFFICE OF ACQ GRANT SVCS Beltsville MD 20705 USA
 
ZIP Code
20705
 
Solicitation Number
FDA-23-1268046
 
Response Due
9/19/2023 9:00:00 AM
 
Archive Date
09/19/2023
 
Point of Contact
Elena Tatarov
 
E-Mail Address
elena.tatarov@fda.hhs.gov
(elena.tatarov@fda.hhs.gov)
 
Description
Request for Quotation: FDA-23-1268046 Posted Date: September 14, 2023 Response Date: September 19, 2023, 12:00 p.m Eastern Time. Interested parties may identify in writing their interest and capability to respond by no later than September 19, 12:00 p.m. Eastern Time. Please email responses to Elena Tatarov at Elena.Tatarov@fda.hhs.gov. Indicate company�s SAM.gov Unique Entity ID on the quote. The subject line shall read: FDA-23-1268046 � ANTI-ANTHRAX TOXIN ANTIBODY, RAXIBACUMAB This is a combined synopsis/solicitation for commercial supplies prepared in accordance with the format in FAR 12.6 as supplemented with FAR 8 and additional information included in this notice. The incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2023-05. This solicitation is issued as a Request for Quote (RFQ). This announcement constitutes the only solicitation; quotes are being requested and a written solicitation will not be issued. The Government intends to issue a Firm Fixed Price Task Order. NAICS Code: 325414 Line Item Structure: The following is a contract line item number(s), quantities, and units of measure, (including option(s), if applicable): Line Item 0001 - FDA-23-1268046 � ANTI-ANTHRAX TOXIN ANTIBODY, RAXIBACUMAB Background Anthrax is a life-threatening disease caused by infection with Bacillus anthracis. The deliberate human use of anthrax has emerged as a biological terrorism threat, highlighted by a series of deadly attacks through the postal service in the form of a finely powdered preparation of anthrax spores in 2001. Anti-anthrax toxin antibodies have been developed as therapeutic for prophylaxis and treatment of inhaled anthrax. Potency control is essential for quality assurance of the anti-anthrax toxin therapeutic antibodies. Our laboratory has been developing a new cell-based potency assay for anti-anthrax toxin therapeutics that reflects the in vivo mechanism of action of the product better than currently available potency assays. This acquisition is for the FDA-approved anti-anthrax toxin antibody, raxibacumab, which is a critical reagent for validation of our new cell-based potency assay.�� System Description U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Lab1 of Division of Biotechnology Review and Research II in Office of Biotechnology Products, need a large amount of the anti-anthrax antibody, raxibacumab, to validate our cell-based potency assay (10 mg). The antibody shall be high quality to ensure success of validation. The antibody will be provided as solution in a glass vial with a concentration of 10 mg/mL. Requirement The Contractor shall provide antibody that have high purity with extremely low level of endotoxin contamination. Deliverables The Contractor shall provide antibody to be delivered as solution in a single glass vial at the concentration of 10 mg/mL. PLEASE SEE ATTACHED RFQ FOR ALL DETAILS.
 
Web Link
SAM.gov Permalink
(https://sam.gov/opp/225b024dcc3d48c78cf461c4e8d9d40e/view)
 
Place of Performance
Address: Silver Spring, MD 20993, USA
Zip Code: 20993
Country: USA
 
Record
SN06832167-F 20230916/230914230125 (samdaily.us)
 
Source
SAM.gov Link to This Notice
(may not be valid after Archive Date)

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