Loren Data's SAM Daily™

SAMDAILY.US - ISSUE OF JANUARY 06, 2024 SAM #8075
SOLICITATION NOTICE

66 -- TSI aerodynamic particle sizer (APS) spectrometer system, catalog # 3321, with software, flow meter and filters

Notice Date

1/4/2024 12:44:58 PM
 

Notice Type

Presolicitation
 

NAICS

334516 — Analytical Laboratory Instrument Manufacturing
 

Contracting Office

NATIONAL INSTITUTES OF HEALTH NIAID BETHESDA MD 20892 USA
 

ZIP Code

20892
 

Solicitation Number

NOI-NIAID-24-2206603
 

Response Due

1/10/2024 2:00:00 PM
 

Archive Date

01/25/2024
 

Point of Contact

Dana Monroe, Phone: 4063759814
 

E-Mail Address

dana.monroe@nih.gov
(dana.monroe@nih.gov)
 

Description

PRE-SOLICITATION NOTICE� ** NOTICE OF INTENT NOI-NIAID-24-2206603 NAICS � 334516, Analytical Laboratory Instrument Mfg This is a Notice of Intent, not a request for proposal.� The National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) Integrated Research Facility (IRF) intends to negotiate on an other than full and open competition basis with TSI Incorporated of Shoreview, MN to procure an additional TSI aerodynamic particle sizer (APS) spectrometer system, catalog # 3321, with software, flow meter and filters, for the continuation of a collaborative project with the National Biodefense Analysis and Countermeasures Center (NBACC) to explore small and large particle aerosol deposition using modalities within the respiratory tract of rodents. The Aerobiology section of the IRF develops aerosol animal models of disease caused by high consequence pathogens within high containment animal biosafety level-4 (ABSL-4) and BSL-4.� Therapeutic and prophylactic agents (e.g. vaccines) are evaluated in these animal models.� Additionally, this section evaluates and compares virus deposition, infectivity, and virulence among animals inoculated with aerosols versus other routes of administration (e.g. intramuscular).� A major focus of this aerosol research is exploring various particle sizes (small, intermediate and large) and monitoring deposition sites within the lower, mid and upper respiratory tract; and comparing subsequent disease course outcomes for potential medical countermeasure development.� To determine the particle size for a specific aerosol run, an APS is required to generate a reading of the actual particles generated and sampled.� This provides the researcher feedback for the aerosol system and shows if desired target particle size is equivalent to the actual particle size.� This TSI brand APS provides a high-resolution, real-time aerodynamic measurement of particles ranging from 0.5 to 20.0 �m, thus encompassing all size ranges affecting the respiratory tract and mucosa.� This APS uses a patented, double-crest optical laser system for sizing accuracy which results in greater small particle sizing efficiency, improved accuracy of mass-weighted distributions and virtual elimination of false background counts. All previous data recorded from the Integrated Research Facility�s aerosol animal models since inception have used these TSI brand APS systems.� Trying to correlate the data between any equipment other than this APS would require several bridging studies to ensure accuracy and proper conversion if this is even applicable. This will be very taxing/costly on facility resources. This APS is what the collaborator used during preliminary testing prior to equipment transfer.� All data acquired is based on collection and analysis using APS technology.� The statutory authority for this sole source requirement is 41 U.S.C. 1901 (a) (1) as implemented by FAR 13.106-1 only one responsible source and no other supply of service will satisfy agency requirements. THIS IS NOT A REQUEST FOR PROPOSAL.� All responsible sources that could provide comparable services may submit a capability statement that will be considered by email (subject line to reference NOI-NIAID-24-2206603) to Dana Monroe at dana.monroe@nih.gov, by 5:00pm eastern daylight savings time Wednesday, January 10, 2024. �All responses received by the closing date of this synopsis will be considered by the Government.� A determination not to compete this requirement, based upon responses to this notice, is solely within the discretion of the Government.
 

Web Link

SAM.gov Permalink
(https://sam.gov/opp/9e0882f5d3d24e898844931455434bd7/view)
 

Place of Performance

Address: Frederick, MD 21702, USA

Zip Code: 21702

Country: USA
 

Record

SN06927456-F 20240106/240104230043 (samdaily.us)
 

Source

SAM.gov Link to This Notice
(may not be valid after Archive Date)

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