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SAMDAILY.US - ISSUE OF SEPTEMBER 28, 2024 SAM #8341
SOLICITATION NOTICE

A -- DNA Methylation & Genome Wide Association assays for evaluating changes in Epigenetic Aging for Veterans with HIV who participated in a Telehealth-delivered High-Intensity Exercise Program

Notice Date
9/26/2024 9:16:31 AM
 
Notice Type
Combined Synopsis/Solicitation
 
NAICS
541715 — Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
 
Contracting Office
RPO EAST (36C24E) PITTSBURGH PA 15212 USA
 
ZIP Code
15212
 
Solicitation Number
36C24E24Q0139
 
Response Due
9/27/2024 6:00:00 AM
 
Archive Date
10/02/2024
 
Point of Contact
Karly Gabrysiak, Contract Specialist, Phone: E-Mail only
 
E-Mail Address
Karly.gabrysiak@va.gov
(Karly.gabrysiak@va.gov)
 
Awardee
null
 
Description
Amendment 1 Answer Vendor Questions for Solicitation 36C24E24Q0139. Question 1: We are performing independent research on the Combined Synopsis/Solicitation (36C24E24Q0139). We would like to know if this is a brand new contract OR if there is (was) an incumbent performing these services. If not brand new, could you please provide the current / previous contract number? Appreciate any insight you can provide. Answer to Question 1: This is new and there is no incumbent performing these services for the Requesting Activity for VA Portland Health Care System. Questions 2-8 were sent in together* Question 2: We utilize a custom EPIC V2 array with additional information. Would that array be appropriate to use for this project or would the standard EPIC V2 array be more appropriate? Answer to Question 2: The standard version of EPIC V2 array is what is planned for use. Question 3: Are the 102 samples to be used for GWAS a subset of the 191 or a separate cohort? In either case, can you help me better understand the expectation for sample processing in Item Number 4? Answer to Question 3: The 102 is a subset of the 191. The sample processing is any required processing to do the required assays only. Question 4: Is there an expectation to use genotyping arrays for the GWAS? If so, is there a preference or would one of the arrays we use for MVP be appropriate? Answer to Question 4: The GWAS array genotyping is part of the study. The MVP array is fine, as well as the Illumina GSA array. Question 5: Would PacBio long read sequencing be considered for the GWAS? Answer to Question 5: No, only the GWAS array for genotyping. See (3) above. Question 6: What should be the disposition of the samples once the assays are finished? Answer to Question 6: If possible, would be best to return to us. Question 7: Is there an expectation for data analysis beyond providing the raw data? Answer to Question 7: No data analysis needed. Question 8: What are the requirements for data delivery? Answer Question 8: Encrypted and sent via secure FTP. Upon award this will be facilitated.
 
Web Link
SAM.gov Permalink
(https://sam.gov/opp/647c45933e9e403b989b3f9042c2952a/view)
 
Place of Performance
Address: USA
Country: USA
 
Record
SN07225977-F 20240928/240926230116 (samdaily.us)
 
Source
SAM.gov Link to This Notice
(may not be valid after Archive Date)

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