Loren Data's SAM Daily™

SAMDAILY.US - ISSUE OF MAY 18, 2025 SAM #8574
SOLICITATION NOTICE

66 -- Automated Dry Heat Diffusion System

Notice Date

5/16/2025 7:18:39 AM
 

Notice Type

Combined Synopsis/Solicitation
 

NAICS

334516 — Analytical Laboratory Instrument Manufacturing
 

Contracting Office

FDA OFFICE OF ACQ GRANT SVCS Beltsville MD 20705 USA
 

ZIP Code

20705
 

Solicitation Number

75F40125Q00181
 

Response Due

5/30/2025 11:00:00 AM
 

Archive Date

06/14/2025
 

Point of Contact

Amanda Lusk, Nicholas Bisher
 

E-Mail Address

Amanda.Lusk@fda.hhs.gov, Nicholas.Bisher@fda.hhs.gov
(Amanda.Lusk@fda.hhs.gov, Nicholas.Bisher@fda.hhs.gov)
 

Description

The Division of Product Quality Research (DPQR) conducts research on assessing the quality and safety of drug products. One of the on-going research activities is to conduct research on assessing the performance, quality and safety of transdermal and topical drug products. These studies are critical in assessing the quality of transdermal and topical drug delivery systems. To support this function, DPQR is requesting the acquisition of one (1) Automated Dry Heat Diffusion System with 24 vertical cells (or equivalent). This Automated Dry Heat Diffusion System will be used to perform diffusion studies that are approximately 96 hours and with large number of samples and repetitions to check the drug release and permeation across synthetic and biological barriers. This Automated Dry Heat Diffusion System and these diffusion studies will provide valuable information regarding safety, performance, and quality of transdermal and drug products and support CDER�s mission critical missions. The Automated Dry Heat Diffusion System with 24 vertical cells is used for studying the in vitro drug release and diffusion across various synthetic and biological barriers. This diffusion system has a heated donor and receiver compartments of the vertical diffusion cells with an automated mechanism to continuously collect and replace aliquot and whole media samples from all diffusion cells. This automated mechanism should also eliminate and expel any air bubbles that may be formed below the diffusion barrier during dosing and sampling throughout the study duration. This Automated Dry Heat Diffusion System is also equipped with sensors for direct measurement and control of donor and receiver chambers and barrier temperatures throughout the study duration.
 

Web Link

SAM.gov Permalink
(https://sam.gov/opp/14b7a4d7b8ed403eb6f86e843e1d0964/view)
 

Place of Performance

Address: Silver Spring, MD 20993, USA

Zip Code: 20993

Country: USA
 

Record

SN07446414-F 20250518/250516230049 (samdaily.us)
 

Source

SAM.gov Link to This Notice
(may not be valid after Archive Date)

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