SAMDaily.us | PRESOL | B | Toxicity evaluation of YC1 in hSULT1A1 and mSULT1A1 mice

SAMDAILY.US - ISSUE OF AUGUST 14, 2025 SAM #8662
SOLICITATION NOTICE

B -- Toxicity evaluation of YC1 in hSULT1A1 and mSULT1A1 mice

Notice Date: 8/12/2025 3:55:22 AM
Notice Type: Presolicitation
NAICS: 541380 — Testing Laboratories
Contracting Office: NATIONAL INSTITUTES OF HEALTH NIDA Bethesda MD 20892 USA
ZIP Code: 20892
Solicitation Number: 75N95025Q00237
Response Due: 8/18/2025 9:00:00 AM
Archive Date: 09/02/2025
Point of Contact: Andrew Varley, Phone: 3018275851, Joshua T. Lazarus, Phone: 3018276923
E-Mail Address: andrew.varley@nih.gov, Josh.Lazarus@nih.gov
(andrew.varley@nih.gov, Josh.Lazarus@nih.gov)
Small Business Set-Aside: NONE No Set aside used
Description: NCATS seeks to determine if YC1 which works with a unique mechanism of cytotoxicity towards cancer cells that express SULT1A1. In doing so, NCATS shall establish the therapeutic window for YC1. To that end NCATS requires head-to-head comparison on YC1 in mice that have humanized SULT1A1 (custom mice available at GemPharmaTech) and with mouse SULT1A1 (wild type).
Web Link: SAM.gov Permalink
(https://sam.gov/opp/9297051a89bc4a30944a0f0465525a52/view)
Place of Performance: Address: Rockville, MD 20850, USA; Zip Code: 20850; Country: USA
Record: SN07546658-F 20250814/250812230044 (samdaily.us)
Source: SAM.gov Link to This Notice
(may not be valid after Archive Date)

| FSG Index | This Issue's Index | Today's SAM Daily Index Page |