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SAMDAILY.US - ISSUE OF APRIL 11, 2026 SAM #8902
SOLICITATION NOTICE

A -- Virtual-Integrated Twin for Autonomous Lifesaving (VITAL)

Notice Date
4/9/2026 2:07:35 PM
 
Notice Type
Solicitation
 
NAICS
541714 — Research and Development in Biotechnology (except Nanobiotechnology)
 
Contracting Office
DEF ADVANCED RESEARCH PROJECTS AGCY ARLINGTON VA 222032114 USA
 
ZIP Code
222032114
 
Solicitation Number
DARPA-PS-26-26
 
Response Due
6/25/2026 4:00:00 PM
 
Archive Date
07/25/2026
 
Point of Contact
Dr. Roozbeh Jafari, Program Manager, DARPA/BTO
 
E-Mail Address
VITAL@darpa.mil
(VITAL@darpa.mil)
 
Description
The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative approaches to address challenges in developing continuously updating digital twin models of the cardiovascular system that combine patient data with biological physics to simulate in real time possible interventions and to predict their outcomes before actual intervention on a patient. The VITAL program will establish a foundation for causal, prediction-driven decision support in medicine, enabling clinicians and future autonomous systems to evaluate treatment options before they are applied. By defining when mechanistic digital twins, reduced-order models, and data-driven inference are reliable and actionable, VITAL will shift medical care from reactive assessment to anticipatory intervention. This capability has the potential to improve outcomes across acute, chronic, and emergent clinical settings.
 
Web Link
SAM.gov Permalink
(https://sam.gov/workspace/contract/opp/5c6a433f8f6c4965a787ef4a01191d72/view)
 
Record
SN07773855-F 20260411/260409230043 (samdaily.us)
 
Source
SAM.gov Link to This Notice
(may not be valid after Archive Date)

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