National Cancer Institute, Research Contracts Branch, TCS, 6120 Executive Blvd, Room 603, MSC 7220, Bethesda Md 20892-7220

R -- DEVELOP, OPERATION & MAINT OF NCI RELATIONAL CHEM DATABASE SOL N02-CM-87008-74 DUE 061697 POC Odessa S. Henderson, Contract Specialist (301)435-3821 or FAX (301) 402-6699 E-MAIL: Odessa Henderson, hendersono@RCB.NCI.NIH.GOV. The Developmental Therapeutics Program (DTP) of the National Cancer Institute's Division of Cancer Treatment, Diagnosis, and Centers (DCTDC) is seeking an organization to provide support for their Drug Information System. This system is used to record drug shipment and structure information for synthetic and natural product compounds that DTP screens for anti-cancer and anti-HIV therapeutic activity. This system serves as a storage and retrieval mechanism for both current and historical data. It is implemented as a client-server architecture consisting of a PC/Microsoft Windows based user interface and an Oracle database server on a DEC10000 Model 720. The user interface is written in Omnis7. The contractor shall take responsibility for the current Drug Information System (DIS) and all of its subsystems. The responsibility shall include design and/or redesign of system programs as well as initial coding, revising, testing, debugging, documentation, operation, and/or maintenance of all system software. The contractor shall also provide support for installation and operation of the systems and development of new hardware/software systems as required for further development of the DTP drug discovery and development programs. The offeror may not be a pharmaceutical, chemical, or biotechnology firm as compound information stored in the DIS is of a proprietary nature. The offeror must be accessible and available for frequent face to face meetings with the DTP DIS user community and Information Technology Branch (ITB). These meetings may be as frequent as once a month. The Principal Investigator and the Senior Analyst should be available for these meetings, which will be conducted with no less than one week's notice. ITB and the DTP DIS user community are located in both Rockville, MD and Frederick, MD and meetings will generally be held in one of these locations. It is anticipated that 5,735 direct labor hours per year will be required for this project and that a single level of effort award will be made for a five year period of performance with incremental funding each year. This is a recompetition of contract NCI-CM-37811 currently performed by Oxford Molecular Group. "See Note 1" (0077)

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