National Institutes of Health, National Institute of Allergy and Infectious Diseases, Contract Management Branch, Solar Bldg., Room 3C07, 6003 Executive Blvd. MSC 7610, Bethesda, MD 20892-7610

A -- GENETIC VARIATION OF HIV-1 AND RELATED LENTIVIRUSES SOL RFP-NIH-NIAID-DAIDS-98-18 DUE 121997 POC Kristiane Cooper, Contract Specialist, (301) 496-7288; E-MAIL: kc116y@nih.gov The Division of AIDS (DAIDS), National Institute of Allergy and Infectious Diseases (NIAID), NIH, has a requirement to carry out large-scale genetic cloning and sequencing of HIV-1 and related lentiviruses. The Contractor will receive samples infected with HIV-1 or related lentiviruses and will be required to genetically clone and sequence genomic fragments and full-length, functional proviruses from these samples. The purpose of this contract is to support the NIAID in its mission to stimulate research towards discovery and testing of prototype vaccines and prevention interventions for the acquired immunodeficiency syndrome (AIDS). This is an announcement for an anticipated Request for Proposals (RFP). It is anticipated that one (1) completion type cost-reimbursement contract for a six-year period of performance will be awarded as a result of this solicitation. RFP NIH-NIAID-DAIDS-98-18 will be available electronically on or about September 29, 1997, and may be accessed through either the NIAID Contract Management (CMB) Home Page or the NIH Gopher by using the following electronic mail addresses and instructions: 1) NIAID/CMB Home Page (via the World Wide Web): Access by using http://www.niaid.nih.gov/contract and select the "RFP" link. 2) To access the NIH Gopher: Point your Gopher client to GOPHER.NIH.GOV.PORT70 (you should now be in the NIH Gopher). Select "Grants and Research Information," then select "R&D Request for Proposals (RFP)," select "RFPs Available," then select NIAID, and select "RFP NIH-NIAID-DAIDS-98-18." PROPOSALS IN RESPONSE TO THIS RFP MUST BE SUBMITTED ELECTRONICALLY. INSTRUCTIONS FOR THIS PROCUREMENT AND FOR PROPER SUBMISSION WILL BE SET FORTH IN THE RFP. Please note that the RFP for this procurement has been revised to include only the Statement of Work, Deliverable and Reporting Requirements, the Technical Evaluation Criteria, and proposal preparation instructions. All information required for the submission of an offer will be contained in the electronic RFP package. Followingproposal submission and the initial review process, Offerors comprising the competitive range will be requested to provide additional documentation to the Contract Specialist. Responses to this RFP will be due no later than 4:30 p.m. (E.S.T.) on December 19, 1997. This advertisement does not commit the Government to award a contract. Point of Contact: Kristiane Cooper, Contract Specialist, Contract Management Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Solar Building, Room 3C07, 6003 Executive Blvd., Bethesda, Maryland 20892. Electronic mail address: kc116y@nih.gov Telephone: (301) 496-7288 FAX: (301) 402-0972. No collect calls will be accepted. All proposals from responsible sources will be considered by the NIAID. (0258)

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