National Institutes of Health, National Institute of Allergy and Infectious Diseases, Contract Management Branch, Solar Bldg., Room 3C07, 6003 Executive Blvd. MSC 7610, Bethesda, MD 20892-7610

A -- COLLABORATIVE NETWORK FOR CLINICAL RESEARCH ON IMMUNE TOLERANCE SOL RFP NIH-NIAID-DAIT-99-30 DUE 061599 POC Rosemary McCabe Hamill, Contracting Officer, (301) 496-0384 The Division of Allergy, Immunology and Transplantation of the National Institute of Allergy and Infectious Diseases (NIAID), NIH, has a requirement for a Contractor having the capabilities and facilities to establish, coordinate and manage a Collaborative Network for Clinical Research on Immune Tolerance. The goals of this Collaborative Network are to: (1) design a long-term research agenda to accelerate the application of tolerogenic approaches for the treatment of multiple immune system diseases, including autoimmune diseases, asthma and allergic diseases, and graft rejection on solid organ, cell and tissue transplantation. Specifically, the Contractor shall design and conduct clinical trials at all phases to evaluate the safety, toxicity and efficacy of promising tolerance induction strategies in these disease areas, and design and conduct studies of the underlying mechanisms involved in the induction, maintenance and loss of tolerance as an integral part of Network-sponsored clinical trials, as well as clinical trials supported by other Federal and private organizations and companies. RFP NIH-NIAID-DAIT-99-30 will be available electronically on or about January 15, 1999, and may be accessed through the NIAID Contract Management Branch (CMB) Homepage by following electronic address and instructions: NIAID-CMB Homepage (via the World Wide Web): Access by: http://www.niaid.nih.gov/contract and select the "RFPs" link. Please note that the RFP for this acquisition has been revised to include only the Research and Technical Objectives, deliverables and reporting requirements, special requirements, and mandatory qualifications, if any, the Technical Evaluation Criteria, and the proposal preparation instructions. All information required for the submission of an offer will be contained in the electronic RFP package. Proposals in response to this RFP will be due on or about June 15, 1999. Any responsible offeror may submit a proposal, which will be considered by the Government. This advertisement does not commit the Government to award a contract. It is anticipated that one cost-reimbursement type contract will be awarded for a period of seven (7) years. Point of Contract: Rosemary McCabe Hamill National Institute of Allergy and Infectious Diseases Contracts Management Branch Solar Building, Room 3C03 6003 Executive Boulevard Bethesda, MD 20892 Electronic Mail Address: rh26v@nih.gov Telephone: (301) 496-0384 Facsimile: (301) 480-5253 Posted 12/31/98 (W-SN284446). (0365)

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