National Cancer Institute, Research Contracts Branch, PSAS, 6120 Executive Blvd, EPS/Room 638, Bethesda, MD 20892-7227

B -- SPECIAL STUDIES AND ANALYSIS- NOT R&D SOL RFQ-NCI-90162 DUE 090299 POC Cynthia Brown, Purchasing Agent, 301-402-4509, Todd Cole, Contracting Officer The National Institutes of Health, National Cancer Institute(NCI) plans to procure services from BioServe Biotechnologies, P.O. Box 17140, Baltimore, MD 21203 to extract DNA from blood clot samples of persons with and without lung cancer (approximately 727 samples). The study is associated with a ZO1 project for molecular epidemiology of lung cancer. In the overarching ZO1 study, biomarkers of lung cancer risk involving alcohol related risk factors are being identified. NCI has available blood cot samples, an appropriate DNA source, that are available for this study. Appropriate scientifically verified extraction procedures shall be used to obtain quality DNA from the aforementioned blood clots. BioServe is the only organization known to NCI researchers that has DNA extraction methods for blood clots scientifically peer reviewed and positive results published in available scientific literature. Without such review and publication, unreviewed methods may affect the integrity of the overall study results. This is not a request for competitive quotation. However, if any interested party believes it possesses this capability and can perform the above requirement, it may submit a statement of capabilities. The statement of capabilities and any other information furnished must be in writing and must contain material in sufficient detail (including evidence of peer review and valid scientific publication of methodology data) to allow NCI to determine if the party can perform this requirement. Capability statements must be received in the contracting office by 3:00 p.m. EST, on September 2, 1999. If you have any questions, please contract Cynthia Brown, Purchasing Agent on (301) 402-4509. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. Posted 08/16/99 (W-SN368155). (0228)

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