A -- VISIBLE HUMAN PROJECT ANATOMICAL METHODS

Notice Date

February 15, 2001

Contracting Office

National Library of Medicine, Office of Acquisitions Management, Building 38A, Room B1N17, 8600 Rockville Pike, Bethesda, Maryland 20894

ZIP Code

20894

Solicitation Number

BAA/RFP NLM 01-106/DJH

Point of Contact

Daniel J. Hartinger, Contracting Officer, 301/496-6546

E-Mail Address

click here to contact the contracting officer via (dh29a@nih.gov)

Description

The National Library of Medicine (NLM), in partnership with the National Institute of Dental and Craniofacial Research (NIDCR), the National Eye Institute (NEI), the National Institute of Deafness and Other Communication Disorders (NIDCD), the National Cancer Institute (NCI), the National Institute of Mental Health (NIMH), the National Institute of Neurological Disorders and Stroke (NINDS), and the National Science Foundation (NSF) seeks to obtain competitive proposals for the award of one or more completion type, cost reimbursement contracts. The goal of the project is to rectify anatomic methodology issues cited as negative outcomes from anatomic observations (lessons learned) of the Visible Human Project (VHP). This project will involve the development of a Visible Human Project Sequential Standard Method to address and solve the anatomic methodology issues, and develop tissue enhancements or markers for neurovascular structure identification. Offerors may submit a research & development contract proposal which includes: (1) Human cadaveric fresh tissue enhanced MRI and CT with fiducial marking or other frames of reference, for the purpose of accurate precise tissue registration and alignment in the acquisition of multimodal imaging data, (2) Establish a set of conditions required for the optimum Visible Human embalming fixation method, (3) Detect vascular structures by luminal filling with a colored substance that possesses physical stability in cold extreme conditions of cryopreservation and cryosectioning of a Visible Human, (4) Determine a chemical marker with the histochemical specificity to detect peripheral nervous system structures (nerves) at cold temperature reaction conditions that differentiate the image of nerves from adjacent tissues, and (5) Develop a digital capture method that includes the testing of polarization of light, intrinsic fluorescence, and multispectral imaging data capture. The contract(s) will result in two types of deliverables: (1) a published standard method for Visible Human tissue preparation and preservation, for the purpose of acquiring Visible Human data; and (2) morphological evidence and scientific data which document the research and development basis of the derived standardized method. Award(s) are anticipated on or about September 28, 2001. The period of performance of the resultant contract(s) is to be 12 months. BAA/RFP NLM 01-106/DJH will be available on or about April 15, 2001. BAA/RFP NLM 01-103/DJH will be available in electronic format only. Paper copies will not be issued. The BAA/RFP may be downloaded from the National Library of Medicine, Office of Acquisitions Management (OAM) home page on the World Wide Web. OAM's URL is http://www.nlm.nih.gov/oam/oam.html. All responsible sources may submit a proposal that will be considered by the National Library of Medicine. Telephone and/or fax requests will not be honored. See Numbered Note 26.

Web Link

click here to download a copy of the BAA/RFP (http://www.nlm.nih.gov/oam/oam.html)

Record

Loren Data Corp. 20010220/ASOL006.HTM (W-046 SN50D8E9)