NATIONAL INSTITUTES OF HEALTH CLINICAL CENTER (NIHCC) OPPORTUNITY FOR COOPERATIVE RESEARCH AND DEVELOPMENT AGREEMENT (CRADA): APPLICATION SPECIFIC COMPUTER-LEARNED MEDICAL-OUTCOME INDEXES.

Notice Date

April 16, 2001

Contracting Office

NIH/TDCB, 6120 Executive Blvd., Suite 450, Rockville, MD 20852

ZIP Code

20852

E-Mail Address

Inquiries and proposals regarding this opportunity (goldsteb@mail.nih.gov)

Description

SUMMARY: The National Institutes of Health Clinical Center (NIHCC) is seeking to enter at least one Cooperative Research and Development Agreement (CRADA). The goal is to develop and implement application specific computer-learned medical-outcome indexes as partially described in the April 2001 issue of the periodical entitled "Advance for Administrators of the Laboratory." SUPPLEMENTARY INFORMATION: A CRADA is not a grant, and is not a contract for the procurement of goods/services. THE NIHCC IS PROHIBITED FROM TRANSFERRING FUNDS TO A CRADA COLLABORATOR. As used here, the expression "computer-learned medical outcome indexes" refers to probability or degree of membership values indicating ('indexing') particular medical outcomes such as diagnostic categories, preferred treatments, times to events, and other medical classifications and outcomes. These indexes and their confidence intervals are computed using laboratory and other patient data with neural networks and other machine-learning computer programs which, once trained, may run as background tasks in laboratory instrument computers, hospital information systems, and various personnel computers including desk, lap, and palm top computers. These programs could also be inscribed in hardware. It is expected that medical index computer programs will provide valuable patient information at virtually no extra cost, and that they will be in everyday use in future clinical settings to aid health care providers in making important cost-effective patient management decisions. The described methods are the subject of an Employee Invention Report filed with the NIH Office of Technology Transfer. Also the initial report and characterization of the invention is partially described in an article entitled "Computer-Learned Medical Outcome Indexes, by Jim DeLeo, in the April 2001 issue of Advance for Administrators of the Laboratory. Commercialization of new CRADA technology may require obtaining an appropriate PHS license to practice this described prior art. The collaborator in this endeavor is expected to commit technical personnel commensurate with the level of research activities defined by the CRADA Research Plan. It is anticipated that PHS facilities and/or those of the collaborator will be utilized, as appropriate, for the research activities as defined by the Research Plan. NIHCC anticipates, in addition, that the Collaborator, as appropriate, will provide funding for the project.

Web Link

Technology Transfer Branch, National Cancer Institute, (http://tdcb.nci.nih.gov)

Record

Loren Data Corp. 20010418/SPMSC006.HTM (W-106 SN50J2X7)