A -- NATIONAL CENTER FOR TOXICOGENOMICS MICROARRAY RESOURCE!!

Notice Date

September 4, 2001

Contracting Office

National Institutes of Environmental Health Sciences, Research Contracts Branch, DERT, P.O. Box 12874, Building 4401, Research Commons, 79 T.W. Alexander Drive, Research Triangle Park, NC 27709

ZIP Code

27709

Solicitation Number

NIH-ES-01-18

Response Due

January 8, 2002

Point of Contact

Jo Ann Lewis, Contracting Officer, (919)541-7894 or email: lewisj@niehs.nih.gov!!

Description

The National Institute of Environmental Health Sciences (NIEHS) is soliciting proposals for the purpose of (1) providing gene expression platforms and protocols for acquiring high quality gene expression data from chemical treated biological systems (Task 1), and (2) providing a gene expression profile database containing analysis and data mining tools (Task 2). In addition, there may be up to four (4) optional studies per year encompassing up to a total of 2400 purified RNA samples (Task 1). Specifically, the Contractor shall establish a gene expression platform that demonstrates utility and validity through data generation and exchange with the NIEHS Microarray Center (NMC); develop standards and practices for incorporation of data from NIEHS extramurally supported consortia; conduct gene expression analysis; develop a database management system; implement a robust data mining tools and public access to store information, computed data and integrated public domain biological resources; and host, maintain, update and secure the database system. Offeror may propose either or both Tasks. One or more awards are anticipated with an award date of August 1, 2002. The period of performance is expected to be five (5) years. For estimating purposes the Government estimates the level-of-effort as follows: Gene Analysis Capabilities (Task 1): 13,832 direct labor hours per year as Senior Professional -- 832 direct labor hours (i.e., Principal Investigator, bioinformatics leader); Other Professionals -- 12,480 direct labor hours (i.e., laboratory technician, computer technician), Administrative Support -- 520 direct labor hours. The Prototype Microarray Gene Expression Database System (Task 2): 15,080 direct labor hours per year as Senior Professional -- 2,080 direct labor hours (i.e., Principal Investigator/Bioinformatics, information technology systems leader); Other Professionals -- 12,480 direct labor hours (i.e., computer technician); and Administrative Support -- 520 direct labor hours. Optional Studies: 13,832 direct labor hours as Senior Professional -- 832 direct labor hours (i.e., Principal Investigator/Bioinformatics leader); Other Professionals -- 12,480 direct labor hours (i.e., computer technician); and Administrative Support -- 520 direct labor hours. The anticipated release date of the RFP is September 24, 2001 with proposals due January 8, 2002. Interested firms should telefax a request for RFP NIH-ES-01-18 to the attention of Ms. Melissa Gentry, Procurement Technician at (919) 541-2712 or send an e-mail request to gentry1@niehs.nih.gov. The electronic version of the CBD synopsis is available on the Internet at http://www.niehs.nih.gov/dert/rcb/rfp.htm. An electronic copy of the RFP will be posted to this site on or about September 18, 2001. This requirement is unrestricted. NAICS is 541710.

Record

Loren Data Corp. 20010906/ASOL002.HTM (W-247 SN50W6Q9)